SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 5b2h HA-33
(Clostridium
botulinum) 		4 / 6 THR A 197
ARG A  10
ILE A 232
LEU A 207
 None
 1.24A 4ac9C-5b2hA:
undetectable		 4ac9C-5b2hA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5b2h HA-33
(Clostridium
botulinum) 		4 / 6 THR A 197
ARG A  10
ILE A 232
LEU A 207
 None
 1.21A 4acaC-5b2hA:
undetectable		 4acaC-5b2hA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5b2h HA-33
(Clostridium
botulinum) 		5 / 11 VAL A  82
ASP A  65
PHE A  16
VAL A  35
THR A  67
 None
 1.45A 4eilA-5b2hA:
undetectable		 4eilA-5b2hA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5b2h HA-33
(Clostridium
botulinum) 		5 / 10 VAL A  82
ASP A  65
PHE A  16
VAL A  35
THR A  67
 None
 1.49A 4kyaC-5b2hA:
undetectable		 4kyaC-5b2hA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5b2h HA-33
(Clostridium
botulinum) 		4 / 5 PHE A 231
THR A 243
GLU A  13
ASN A   7
 None
 1.30A 5ybbA-5b2hA:
undetectable		 5ybbA-5b2hA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5b2h HA-33
(Clostridium
botulinum) 		3 / 3 LYS A 252
VAL A 269
ASP A 271
 None
 0.58A 6fgdA-5b2hA:
undetectable		 6fgdA-5b2hA:
20.29