SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZI9_A_CL9A401_2 (DEOXYCYTIDINE KINASE)	5b39	KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1 (Homo sapiens)	3 / 3	ASP G 258 PHE G 259 LEU G 261	None	0.61A	2zi9A-5b39G: undetectable	2zi9A-5b39G: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	5b39	KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1 (Homo sapiens)	3 / 3	ASP G 142 LYS G 136 LEU G 168	None	1.03A	4ptjA-5b39G: undetectable	4ptjA-5b39G: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WAN_C_ACTC303_0 (BRANCHPOINT-BRIDGING PROTEIN)	5b39	KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1 (Homo sapiens)	3 / 3	ASP G 193 ARG G 173 PRO G 191	None	1.08A	4wanC-5b39G: undetectable	4wanC-5b39G: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DK1_C_GM4C301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	5b39	KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1 (Homo sapiens)	5 / 11	VAL G 92 ALA G 16 LEU G 39 THR G 25 ALA G 12	None	1.41A	6dk1C-5b39G: undetectable	6dk1C-5b39G: 20.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZI9_A_CL9A401_2","DEOXYCYTIDINE KINASE","5b39","KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1","Homo sapiens",3,"ASP G 258;PHE G 259;LEU G 261","None","0.61A","2zi9A-5b39G:undetectable","2zi9A-5b39G:20.38"],["4PTJ_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","5b39","KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1","Homo sapiens",3,"ASP G 142;LYS G 136;LEU G 168","None","1.03A","4ptjA-5b39G:undetectable","4ptjA-5b39G:18.52"],["4WAN_C_ACTC303_0","BRANCHPOINT-BRIDGING PROTEIN","5b39","KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1","Homo sapiens",3,"ASP G 193;ARG G 173;PRO G 191","None","1.08A","4wanC-5b39G:undetectable","4wanC-5b39G:17.67"],["6DK1_C_GM4C301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","5b39","KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1","Homo sapiens",5,"VAL G  92;ALA G  16;LEU G  39;THR G  25;ALA G  12","None","1.41A","6dk1C-5b39G:undetectable","6dk1C-5b39G:20.20"]]