SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.58A 1av2C-5b3gB:
undetectable
1av2D-5b3gB:
undetectable		 1av2C-5b3gB:
5.75
1av2D-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 VAL B 225
TRP B 234
TRP B 425
 None
 1.30A 1c4dA-5b3gB:
undetectable
1c4dB-5b3gB:
undetectable		 1c4dA-5b3gB:
5.75
1c4dB-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 TRP B 528
ALA B 525
VAL B 388
 None
 0.88A 1c4dA-5b3gB:
undetectable
1c4dB-5b3gB:
undetectable		 1c4dA-5b3gB:
5.75
1c4dB-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 4 VAL B 389
TRP B 528
ALA B 527
VAL B 388
 None
 1.12A 1gmkA-5b3gB:
undetectable
1gmkB-5b3gB:
undetectable		 1gmkA-5b3gB:
5.75
1gmkB-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 ASN B 356
LEU B 272
ALA B 275
LEU B 276
 None
 1.06A 1hwiC-5b3gB:
undetectable		 1hwiC-5b3gB:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 ILE B 513
GLY B 238
TRP B 269
GLY B 244
TYR B 482
 None
 1.19A 1kiaB-5b3gB:
11.5		 1kiaB-5b3gB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 ILE B 513
GLY B 238
VAL B 490
TRP B 269
TYR B 482
 None
 1.26A 1nbhA-5b3gB:
10.8		 1nbhA-5b3gB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 ILE B 513
GLY B 238
VAL B 490
TRP B 269
TYR B 482
 None
 1.26A 1nbhC-5b3gB:
9.1		 1nbhC-5b3gB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 525
VAL B 388
TRP B 468
 None
 0.97A 1tkqA-5b3gB:
undetectable		 1tkqA-5b3gB:
2.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.60A 1w5uC-5b3gB:
undetectable
1w5uD-5b3gB:
undetectable		 1w5uC-5b3gB:
5.75
1w5uD-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 TRP B 234
ALA B 393
VAL B 522
 None
 0.74A 2izqA-5b3gB:
undetectable
2izqB-5b3gB:
undetectable		 2izqA-5b3gB:
5.75
2izqB-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 10 ILE B 385
LEU B 272
VAL B 250
ALA B 249
VAL B 486
 None
 1.02A 2nnjA-5b3gB:
undetectable		 2nnjA-5b3gB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 ILE B 261
VAL B 291
PHE B 340
ASP B 341
GLU B 344
 None
 1.41A 2qeoA-5b3gB:
undetectable		 2qeoA-5b3gB:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.72A 3l8lA-5b3gB:
undetectable
3l8lB-5b3gB:
undetectable		 3l8lA-5b3gB:
5.75
3l8lB-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.62A 3l8lC-5b3gB:
undetectable
3l8lD-5b3gB:
undetectable		 3l8lC-5b3gB:
5.75
3l8lD-5b3gB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 10 GLY B 335
ASN B 295
GLY B 363
ILE B 364
VAL B 291
 None
 0.93A 3lzvA-5b3gB:
undetectable		 3lzvA-5b3gB:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.53A 3r9tA-5b3gB:
undetectable		 3r9tA-5b3gB:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 7 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.57A 3r9tB-5b3gB:
undetectable		 3r9tB-5b3gB:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 ILE B 256
LEU B 286
ALA B 275
THR B 278
VAL B 324
 None
 1.08A 3rukA-5b3gB:
undetectable		 3rukA-5b3gB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 GLY B 335
ASN B 295
GLY B 363
ILE B 364
VAL B 291
 None
 0.96A 3ucbA-5b3gB:
undetectable		 3ucbA-5b3gB:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 ARG B 461
GLU B 463
LYS B 467
ARG B 471
 None
 1.25A 4bqfB-5b3gB:
undetectable		 4bqfB-5b3gB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 9 LEU B 172
SER B 173
LEU B 188
ALA B 143
LEU B 147
 None
 1.11A 4rs0A-5b3gB:
undetectable		 4rs0A-5b3gB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 10 HIS B 239
GLN B 229
VAL B 225
PHE B 265
THR B 267
 None
None
None
PEG  B 602 (-3.5A)
None
 1.30A 4twlB-5b3gB:
undetectable		 4twlB-5b3gB:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 GLU B 485
LEU B 276
PRO B 284
LEU B 286
ALA B 354
 None
 0.98A 4wcxC-5b3gB:
2.6		 4wcxC-5b3gB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 7 ILE B 385
TYR B 482
ALA B 242
ILE B 246
 None
 0.84A 4y03A-5b3gB:
undetectable		 4y03A-5b3gB:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 5b3g PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ARG B 371
LYS B 296
ARG B 471
 None
 1.07A 6az3C-5b3gB:
undetectable
6az3L-5b3gB:
undetectable
6az3M-5b3gB:
undetectable		 6az3C-5b3gB:
10.32
6az3L-5b3gB:
9.50
6az3M-5b3gB:
9.47