SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.62A 1av2C-5b3hB:
undetectable
1av2D-5b3hB:
undetectable		 1av2C-5b3hB:
5.75
1av2D-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 TRP B 528
ALA B 525
VAL B 388
 None
 0.92A 1c4dA-5b3hB:
undetectable
1c4dB-5b3hB:
undetectable		 1c4dA-5b3hB:
5.75
1c4dB-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		3 / 3 ALA A 387
VAL A 517
TRP A 649
 None
 0.93A 1c4dC-5b3hA:
undetectable
1c4dD-5b3hA:
undetectable		 1c4dC-5b3hA:
9.76
1c4dD-5b3hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		3 / 3 ALA A 387
VAL A 519
TRP A 649
 None
 0.95A 1c4dC-5b3hA:
undetectable
1c4dD-5b3hA:
undetectable		 1c4dC-5b3hA:
9.76
1c4dD-5b3hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 4 VAL A 520
TRP A 649
ALA A 648
VAL A 519
 None
 1.13A 1gmkA-5b3hA:
undetectable
1gmkB-5b3hA:
undetectable		 1gmkA-5b3hA:
9.76
1gmkB-5b3hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 4 VAL B 389
TRP B 528
ALA B 527
VAL B 388
 None
 1.16A 1gmkA-5b3hB:
undetectable
1gmkB-5b3hB:
undetectable		 1gmkA-5b3hB:
5.75
1gmkB-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 ASN B 356
LEU B 272
ALA B 275
LEU B 276
 None
 0.95A 1hwiB-5b3hB:
undetectable		 1hwiB-5b3hB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 ASN B 356
LEU B 272
ALA B 275
LEU B 276
 None
 0.95A 1hwiC-5b3hB:
undetectable		 1hwiC-5b3hB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 12 TYR A 625
ALA A 543
SER A 547
GLY A 549
LEU A 548
 None
 1.11A 1igxA-5b3hA:
undetectable		 1igxA-5b3hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_A_CLWA906_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 5b3h PROTEIN SCARECROW
PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 5 PRO A 322
VAL A 330
TYR B 176
GLU A 336
 None
 1.40A 1m9jA-5b3hA:
undetectable		 1m9jA-5b3hA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.88A 1nt6A-5b3hB:
undetectable		 1nt6A-5b3hB:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.88A 1nt6B-5b3hB:
undetectable		 1nt6B-5b3hB:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 525
VAL B 388
TRP B 468
 None
 1.02A 1tkqA-5b3hB:
undetectable		 1tkqA-5b3hB:
2.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.63A 1w5uC-5b3hB:
undetectable
1w5uD-5b3hB:
undetectable		 1w5uC-5b3hB:
5.75
1w5uD-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 6 VAL A 488
LEU A 406
PHE A 600
MET A 595
 None
 1.02A 1wrlB-5b3hA:
undetectable		 1wrlB-5b3hA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 7 PHE A 370
LEU A 524
PHE A 373
SER A 383
 None
 1.18A 1wrlE-5b3hA:
undetectable		 1wrlE-5b3hA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 12 ILE A 391
ALA A 387
LEU A 433
ILE A 408
PHE A 395
 None
 1.29A 1y0xX-5b3hA:
undetectable		 1y0xX-5b3hA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 6 LEU A 644
LEU A 636
LEU A 544
LEU A 524
 None
 0.83A 2ab2A-5b3hA:
undetectable		 2ab2A-5b3hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 TRP B 234
ALA B 393
VAL B 522
 None
 0.70A 2izqA-5b3hB:
undetectable
2izqB-5b3hB:
undetectable		 2izqA-5b3hB:
5.75
2izqB-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 10 ILE B 385
LEU B 272
VAL B 250
ALA B 249
VAL B 486
 None
 1.07A 2nnjA-5b3hB:
undetectable		 2nnjA-5b3hB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 7 TRP A 490
VAL A 470
THR A 505
LEU A 509
 None
 1.20A 3arrA-5b3hA:
undetectable		 3arrA-5b3hA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ARG B 529
GLU B 248
ASP B 488
 None
 0.90A 3g2oA-5b3hB:
5.7		 3g2oA-5b3hB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA703_1
(CARBONIC ANHYDRASE 2)		 5b3h ZINC FINGER PROTEIN
JACKDAW
(Arabidopsis
thaliana) 		4 / 5 HIS C 177
TRP C 174
TRP C 159
ASP C 173
 ZN  C 302 (-3.5A)
None
None
None
 1.46A 3hs4A-5b3hC:
0.0		 3hs4A-5b3hC:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ASN B 139
ASP B 144
ARG B 431
 None
 0.87A 3k13C-5b3hB:
undetectable		 3k13C-5b3hB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 7 GLY A 416
PHE A 418
PHE A 463
PHE A 461
 None
 0.97A 3ko0D-5b3hA:
2.2
3ko0E-5b3hA:
2.3		 3ko0D-5b3hA:
15.18
3ko0E-5b3hA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 7 GLY B 359
CYH B 507
GLY B 238
PHE B 237
 None
 0.99A 3ko0M-5b3hB:
undetectable
3ko0P-5b3hB:
undetectable		 3ko0M-5b3hB:
13.06
3ko0P-5b3hB:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.69A 3l8lA-5b3hB:
undetectable
3l8lB-5b3hB:
undetectable		 3l8lA-5b3hB:
5.75
3l8lB-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ALA B 393
VAL B 522
TRP B 234
 None
 0.68A 3l8lC-5b3hB:
undetectable
3l8lD-5b3hB:
undetectable		 3l8lC-5b3hB:
5.75
3l8lD-5b3hB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 10 GLU A 484
VAL A 486
LEU A 512
ARG A 432
LEU A 436
 None
 1.49A 3qeoA-5b3hA:
undetectable		 3qeoA-5b3hA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 8 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.71A 3r9tA-5b3hB:
undetectable		 3r9tA-5b3hB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 7 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.72A 3r9tB-5b3hB:
undetectable		 3r9tB-5b3hB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 TYR B 203
GLU B 200
GLY B 199
ALA B 452
SER B 456
 None
 1.39A 3s8pB-5b3hB:
undetectable		 3s8pB-5b3hB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 TYR B 203
GLU B 200
GLY B 199
ALA B 452
SER B 456
 None
 1.37A 4bupA-5b3hB:
undetectable		 4bupA-5b3hB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 5b3h PROTEIN SHORT-ROOT
ZINC FINGER PROTEIN
JACKDAW
(Arabidopsis
thaliana) 		4 / 5 PHE B 218
PHE C 206
ILE B 311
THR B 267
 None
 1.02A 4ejjC-5b3hB:
undetectable		 4ejjC-5b3hB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 4 SER A 383
ASP A 407
MET A 409
ASP A 497
 None
 1.36A 4iv0A-5b3hA:
9.4		 4iv0A-5b3hA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.16A 4mm5A-5b3hA:
undetectable		 4mm5A-5b3hA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 11 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.24A 4mm9A-5b3hA:
undetectable		 4mm9A-5b3hA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.12A 4mmbA-5b3hA:
undetectable		 4mmbA-5b3hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.22A 4mmeA-5b3hA:
undetectable		 4mmeA-5b3hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.27A 4mmeB-5b3hA:
undetectable		 4mmeB-5b3hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.21A 4mmfA-5b3hA:
undetectable		 4mmfA-5b3hA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 VAL A 517
ALA A 648
GLY A 599
PHE A 600
GLY A 602
 None
 1.20A 4mmfB-5b3hA:
undetectable		 4mmfB-5b3hA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 4 SER A 383
ASP A 407
MET A 409
ASP A 497
 None
 1.35A 4mwzB-5b3hA:
9.3		 4mwzB-5b3hA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 12 LEU A 412
GLY A 411
LEU A 450
ILE A 403
VAL A 431
 None
 1.01A 4ok1A-5b3hA:
undetectable		 4ok1A-5b3hA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 9 ALA A 298
ALA A 300
LEU A 306
SER A 529
LEU A 531
 None
 1.34A 4or0A-5b3hA:
2.7		 4or0A-5b3hA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		4 / 4 ASN A 374
LEU A 548
PHE A 382
TYR A 625
 None
 1.42A 4u14A-5b3hA:
undetectable		 4u14A-5b3hA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 12 GLU B 485
LEU B 276
PRO B 284
LEU B 286
ALA B 354
 None
 1.07A 4wcxC-5b3hB:
2.6		 4wcxC-5b3hB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		5 / 11 ASP B 484
ALA B 241
VAL B 490
GLY B 481
GLY B 244
 None
 1.28A 4xnxA-5b3hB:
undetectable		 4xnxA-5b3hB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 5b3h PROTEIN SCARECROW
PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 7 SER A 317
PRO A 322
TYR A 323
SER B 185
 None
 1.24A 5l1fC-5b3hA:
3.9		 5l1fC-5b3hA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 10 ALA A 613
THR A 614
ALA A 606
GLY A 607
ALA A 609
 None
 1.10A 5lf3H-5b3hA:
undetectable
5lf3I-5b3hA:
undetectable		 5lf3H-5b3hA:
21.78
5lf3I-5b3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 10 ALA A 613
THR A 614
ALA A 606
GLY A 607
ALA A 609
 None
 1.11A 5lf3V-5b3hA:
undetectable
5lf3W-5b3hA:
undetectable		 5lf3V-5b3hA:
21.78
5lf3W-5b3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 11 ALA A 613
THR A 614
ALA A 606
GLY A 607
ALA A 609
 None
 1.12A 5lf7H-5b3hA:
undetectable
5lf7I-5b3hA:
undetectable		 5lf7H-5b3hA:
21.78
5lf7I-5b3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5b3h PROTEIN SCARECROW
(Arabidopsis
thaliana) 		5 / 11 ALA A 613
THR A 614
ALA A 606
GLY A 607
ALA A 609
 None
 1.12A 5lf7V-5b3hA:
undetectable
5lf7W-5b3hA:
undetectable		 5lf7V-5b3hA:
21.78
5lf7W-5b3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		3 / 3 ARG B 379
ARG B 529
ARG B 473
 None
 0.77A 5vcgA-5b3hB:
undetectable		 5vcgA-5b3hB:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 6 ILE B 385
LEU B 286
HIS B 257
PHE B 318
 None
 1.05A 5vkqA-5b3hB:
undetectable
5vkqB-5b3hB:
undetectable		 5vkqA-5b3hB:
14.10
5vkqB-5b3hB:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5b3h PROTEIN SHORT-ROOT
(Arabidopsis
thaliana) 		4 / 6 PHE B 318
ILE B 385
LEU B 286
HIS B 257
 None
 1.04A 5vkqA-5b3hB:
undetectable
5vkqD-5b3hB:
undetectable		 5vkqA-5b3hB:
14.10
5vkqD-5b3hB:
14.10