SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
CYH A 124
LYS A 125
HIS A 128
 HEM  A 201 (-3.6A)
HEM  A 201 (-1.8A)
None
HEM  A 201 (-3.4A)
 0.98A 2yldA-5b3iA:
17.4		 2yldA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.13A 2yldA-5b3iA:
17.4		 2yldA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.18A 2ylgA-5b3iA:
17.5		 2ylgA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
CYH A 124
LYS A 125
HIS A 128
 HEM  A 201 (-3.6A)
HEM  A 201 (-1.8A)
None
HEM  A 201 (-3.4A)
 1.07A 3zwiA-5b3iA:
17.4		 3zwiA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.14A 3zwiA-5b3iA:
17.4		 3zwiA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 4 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.15A 4cipA-5b3iA:
17.4		 4cipA-5b3iA:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 8 ILE A 113
PHE A 117
LYS A 122
GLY A 121
 None
 0.82A 4hdlA-5b3iA:
undetectable		 4hdlA-5b3iA:
21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
CYH A 124
LYS A 125
HIS A 128
 HEM  A 201 (-3.6A)
HEM  A 201 (-1.8A)
None
HEM  A 201 (-3.4A)
 1.22A 5jliA-5b3iA:
17.7		 5jliA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.14A 5jliA-5b3iA:
17.7		 5jliA-5b3iA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 4 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.14A 5jslA-5b3iA:
17.6		 5jslA-5b3iA:
34.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		4 / 5 ALA A  20
GLY A 121
CYH A 124
HIS A 128
 HEM  A 201 (-3.6A)
None
HEM  A 201 (-1.8A)
HEM  A 201 (-3.4A)
 0.17A 5jt4A-5b3iA:
17.4		 5jt4A-5b3iA:
34.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5b3i CYTOCHROME C PRIME
(Hydrogenophilus
thermoluteolus) 		5 / 12 LEU A 101
ASP A 109
GLY A 108
ALA A  45
VAL A  30
 None
 1.40A 5kbwB-5b3iA:
2.6		 5kbwB-5b3iA:
22.53