SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		4 / 7 THR A  13
THR A  57
GLY A  92
ASP A  93
 SO4  A 201 (-3.9A)
None
None
None
 0.74A 1bu5A-5b3kA:
20.1		 1bu5A-5b3kA:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		4 / 8 THR A  13
THR A  57
GLY A  92
ASP A  93
 SO4  A 201 (-3.9A)
None
None
None
 0.73A 1bu5B-5b3kA:
20.0		 1bu5B-5b3kA:
31.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 125
ALA A 101
LEU A  91
SER A  56
 None
None
None
SO4  A 201 (-2.8A)
 1.09A 1tt6B-5b3kA:
undetectable		 1tt6B-5b3kA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  52
LEU A 148
ALA A  32
LEU A  30
ALA A  28
 None
 1.29A 2vcvE-5b3kA:
undetectable		 2vcvE-5b3kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  52
LEU A 148
ALA A  32
LEU A  30
ALA A  28
 None
 1.24A 2vcvI-5b3kA:
undetectable		 2vcvI-5b3kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 LEU A   6
LEU A  67
LEU A 110
GLY A  86
LEU A  52
 None
 1.12A 3olsA-5b3kA:
undetectable		 3olsA-5b3kA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		3 / 3 PHE A 100
TYR A  96
LEU A 123
 None
 0.73A 3sueB-5b3kA:
undetectable		 3sueB-5b3kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 10 THR A  55
ALA A 127
GLY A 103
GLY A 102
ALA A 101
 None
 1.04A 4qvpK-5b3kA:
undetectable
4qvpL-5b3kA:
undetectable		 4qvpK-5b3kA:
22.27
4qvpL-5b3kA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 10 THR A  55
ALA A 127
GLY A 103
GLY A 102
ALA A 101
 None
 1.03A 4qvpY-5b3kA:
undetectable
4qvpZ-5b3kA:
undetectable		 4qvpY-5b3kA:
22.27
4qvpZ-5b3kA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 11 THR A  55
ALA A 127
GLY A 103
GLY A 102
ALA A 101
 None
 1.04A 4qw1K-5b3kA:
undetectable
4qw1L-5b3kA:
undetectable		 4qw1K-5b3kA:
22.37
4qw1L-5b3kA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 10 THR A  55
ALA A 127
GLY A 103
GLY A 102
ALA A 101
 None
 1.04A 4qw1Y-5b3kA:
undetectable
4qw1Z-5b3kA:
undetectable		 4qw1Y-5b3kA:
22.37
4qw1Z-5b3kA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		4 / 6 SER A  39
LEU A  40
ASP A  41
LEU A  70
 None
 0.75A 4wozA-5b3kA:
undetectable
4wozB-5b3kA:
undetectable		 4wozA-5b3kA:
19.41
4wozB-5b3kA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  78
LEU A  63
LEU A  67
PHE A 111
GLU A 113
 None
 1.22A 5ieoA-5b3kA:
undetectable		 5ieoA-5b3kA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  78
LEU A  63
LEU A  67
PHE A 111
GLU A 113
 None
 1.23A 5iepA-5b3kA:
undetectable		 5iepA-5b3kA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 THR A  58
ALA A  14
ALA A  18
GLY A   8
PRO A  36
 None
SO4  A 201 (-3.5A)
None
None
None
 1.02A 5jglA-5b3kA:
2.2		 5jglA-5b3kA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 107
LEU A 141
LEU A  52
GLY A  92
LEU A  91
 None
 0.86A 6b0iB-5b3kA:
undetectable		 6b0iB-5b3kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 107
LEU A 141
LEU A  52
GLY A  92
LEU A  91
 None
 1.01A 6b0lB-5b3kA:
undetectable		 6b0lB-5b3kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5b3k UNCHARACTERIZED
PROTEIN PA3435
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  49
LEU A  84
ARG A 117
 None
 0.79A 6d8fA-5b3kA:
2.4		 6d8fA-5b3kA:
12.47