SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 8 HIS A  95
HIS A 157
HIS A  97
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.0A)
ZN  A2002 ( 3.0A)
 1.04A 1azmA-5b3rA:
undetectable		 1azmA-5b3rA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		3 / 3 SER A 197
HIS A  95
ASP A 127
 None
ZN  A2001 ( 3.4A)
None
 0.85A 2oxtA-5b3rA:
undetectable		 2oxtA-5b3rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.28A 2zj0A-5b3rA:
3.0		 2zj0A-5b3rA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.22A 3ce6A-5b3rA:
2.9		 3ce6A-5b3rA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 12 ALA A 132
ILE A  92
GLY A  90
THR A  67
PRO A  68
ILE A 104
 None
 1.48A 3d1xA-5b3rA:
undetectable		 3d1xA-5b3rA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.18A 3g1uA-5b3rA:
3.1		 3g1uA-5b3rA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.21A 3g1uC-5b3rA:
2.9		 3g1uC-5b3rA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.20A 3glqA-5b3rA:
2.9		 3glqA-5b3rA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.19A 3glqB-5b3rA:
2.8		 3glqB-5b3rA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.17A 3n58A-5b3rA:
3.3		 3n58A-5b3rA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 171
ALA A 208
ALA A 221
VAL A  56
ILE A  65
 None
 1.27A 3uvvB-5b3rA:
undetectable		 3uvvB-5b3rA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 8 HIS A  95
HIS A 157
HIS A  97
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.0A)
ZN  A2002 ( 3.0A)
 1.04A 3w6hA-5b3rA:
undetectable		 3w6hA-5b3rA:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_A_X8ZA350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 9 HIS A  97
ASP A  99
HIS A 157
CYH A 176
ASN A 185
HIS A 215
 ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.31A 4c1dA-5b3rA:
31.7		 4c1dA-5b3rA:
31.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		7 / 10 HIS A  95
HIS A  97
ASP A  99
HIS A 157
CYH A 176
ASN A 185
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.38A 4c1dB-5b3rA:
31.6		 4c1dB-5b3rA:
31.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		7 / 11 HIS A  95
HIS A  97
ASP A  99
HIS A 157
CYH A 176
LYS A 179
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-2.6A)
ZN  A2002 ( 3.0A)
 0.28A 4c1fA-5b3rA:
39.6
4c1fB-5b3rA:
38.4		 4c1fA-5b3rA:
82.89
4c1fB-5b3rA:
82.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 11 HIS A  95
HIS A  97
HIS A 157
LYS A 179
ASN A 185
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
ZN  A2001 ( 3.3A)
CIT  A2003 (-2.6A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.70A 4c1fA-5b3rA:
39.6
4c1fB-5b3rA:
38.4		 4c1fA-5b3rA:
82.89
4c1fB-5b3rA:
82.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  49
HIS A  95
HIS A  97
ASP A  99
HIS A 157
 None
ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
 1.13A 4c1fA-5b3rA:
39.6
4c1fB-5b3rA:
38.4		 4c1fA-5b3rA:
82.89
4c1fB-5b3rA:
82.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  49
HIS A  95
HIS A  97
HIS A 157
ASN A 185
 None
ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
ZN  A2001 ( 3.3A)
CIT  A2003 (-4.0A)
 1.08A 4c1fA-5b3rA:
39.6
4c1fB-5b3rA:
38.4		 4c1fA-5b3rA:
82.89
4c1fB-5b3rA:
82.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		7 / 9 HIS A  95
HIS A  97
ASP A  99
HIS A 157
CYH A 176
GLY A 184
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-3.6A)
ZN  A2002 ( 3.0A)
 0.68A 4c1hA-5b3rA:
31.3		 4c1hA-5b3rA:
35.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 11 THR A 114
ALA A 132
LEU A 124
SER A  91
ILE A  65
 None
 1.40A 4claA-5b3rA:
undetectable		 4claA-5b3rA:
22.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 9 VAL A  49
HIS A  97
ASP A  99
HIS A 157
CYH A 176
HIS A 215
 None
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
ZN  A2002 ( 3.0A)
 0.67A 4exsA-5b3rA:
30.5		 4exsA-5b3rA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		7 / 8 VAL A  49
HIS A  97
ASP A  99
HIS A 157
CYH A 176
ASN A 185
HIS A 215
 None
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.74A 4exsB-5b3rA:
31.2		 4exsB-5b3rA:
33.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 6 THR A 158
GLY A 156
ASN A 161
GLY A 184
 None
None
None
CIT  A2003 (-3.6A)
 0.90A 4fjpA-5b3rA:
undetectable		 4fjpA-5b3rA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.16A 4lvcA-5b3rA:
3.0		 4lvcA-5b3rA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.13A 4lvcC-5b3rA:
2.9		 4lvcC-5b3rA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  54
SER A 213
LEU A 172
LEU A  30
 None
 0.95A 4n09A-5b3rA:
undetectable		 4n09A-5b3rA:
20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		7 / 8 VAL A  49
HIS A  97
ASP A  99
HIS A 157
CYH A 176
ASN A 185
HIS A 215
 None
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.59A 5a5zA-5b3rA:
12.3		 5a5zA-5b3rA:
33.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 7 HIS A 157
CYH A 176
LYS A 179
GLY A 184
ASN A 185
HIS A 215
 ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-2.6A)
CIT  A2003 (-3.6A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.49A 5a5zC-5b3rA:
30.9		 5a5zC-5b3rA:
33.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  95
HIS A  97
ASP A  99
HIS A 157
HIS A 215
 ZN  A2001 ( 3.4A)
ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 3.0A)
 0.87A 5ayaA-5b3rA:
17.4		 5ayaA-5b3rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  64
ILE A  65
GLY A  90
ILE A 148
 None
 0.84A 5dzk3-5b3rA:
undetectable
5dzkm-5b3rA:
undetectable		 5dzk3-5b3rA:
1.89
5dzkm-5b3rA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 ILE A  65
GLY A  90
ILE A 148
LEU A  64
 None
 0.93A 5dzkd-5b3rA:
undetectable
5dzkk-5b3rA:
undetectable
5dzky-5b3rA:
undetectable		 5dzkd-5b3rA:
20.88
5dzkk-5b3rA:
22.27
5dzky-5b3rA:
1.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 ILE A  65
GLY A  90
ILE A 148
LEU A  64
 None
 0.88A 5dzkl-5b3rA:
undetectable
5dzkz-5b3rA:
undetectable		 5dzkl-5b3rA:
22.27
5dzkz-5b3rA:
1.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		3 / 3 THR A 120
ALA A 116
ASN A 121
 None
 0.61A 5ersA-5b3rA:
undetectable		 5ersA-5b3rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 132
ILE A  92
GLY A  90
ILE A 112
PRO A  68
 None
 1.23A 5kr2C-5b3rA:
undetectable		 5kr2C-5b3rA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 7 HIS A 215
HIS A 157
HIS A  95
SER A 100
 ZN  A2002 ( 3.0A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.4A)
None
 0.96A 5m8rA-5b3rA:
undetectable		 5m8rA-5b3rA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 215
HIS A 157
HIS A  95
SER A 100
 ZN  A2002 ( 3.0A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.4A)
None
 0.96A 5m8rB-5b3rA:
undetectable		 5m8rB-5b3rA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 215
HIS A 157
HIS A  95
SER A 100
 ZN  A2002 ( 3.0A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.4A)
None
 0.96A 5m8rC-5b3rA:
undetectable		 5m8rC-5b3rA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 215
HIS A 157
HIS A  95
SER A 100
 ZN  A2002 ( 3.0A)
ZN  A2001 ( 3.3A)
ZN  A2001 ( 3.4A)
None
 1.01A 5m8rD-5b3rA:
undetectable		 5m8rD-5b3rA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  84
GLU A  83
TRP A  80
 None
 0.90A 5odiD-5b3rA:
undetectable		 5odiD-5b3rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  84
GLU A  83
TRP A  80
 None
 0.88A 5odqD-5b3rA:
undetectable		 5odqD-5b3rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  84
GLU A  83
TRP A  80
 None
 0.85A 5odrD-5b3rA:
undetectable		 5odrD-5b3rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  57
TYR A  35
ILE A  27
PHE A  81
ASN A  60
 None
 1.11A 5y7pB-5b3rA:
undetectable		 5y7pB-5b3rA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  57
TYR A  35
ILE A  27
PHE A  81
ASN A  60
 None
 1.06A 5y7pD-5b3rA:
undetectable		 5y7pD-5b3rA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  57
TYR A  35
ILE A  27
PHE A  81
ASN A  60
 None
 1.05A 5y7pH-5b3rA:
undetectable		 5y7pH-5b3rA:
22.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		6 / 8 HIS A  97
ASP A  99
HIS A 157
CYH A 176
ASN A 185
HIS A 215
 ZN  A2001 ( 3.0A)
CIT  A2003 ( 2.7A)
ZN  A2001 ( 3.3A)
ZN  A2002 ( 2.2A)
CIT  A2003 (-4.0A)
ZN  A2002 ( 3.0A)
 0.37A 5zj8A-5b3rA:
15.2		 5zj8A-5b3rA:
32.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.14A 6aphA-5b3rA:
3.0		 6aphA-5b3rA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.24A 6f3nA-5b3rA:
3.3		 6f3nA-5b3rA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.25A 6f3nC-5b3rA:
3.3		 6f3nC-5b3rA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 4 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.24A 6f3nD-5b3rA:
3.0		 6f3nD-5b3rA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.16A 6gbnA-5b3rA:
2.8		 6gbnA-5b3rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.17A 6gbnB-5b3rA:
2.9		 6gbnB-5b3rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.17A 6gbnC-5b3rA:
2.7		 6gbnC-5b3rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 5b3r IMP-18
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 230
THR A 227
THR A 158
HIS A  95
 None
None
None
ZN  A2001 ( 3.4A)
 1.19A 6gbnD-5b3rA:
2.5		 6gbnD-5b3rA:
20.37