SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE B 189
ALA B 153
ALA B 231
ARG B 154
LEU B 179
 None
 1.24A 1cbrA-5b3vB:
undetectable		 1cbrA-5b3vB:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE B 189
ALA B 153
ALA B 231
ARG B 154
LEU B 179
 None
 1.24A 1cbrB-5b3vB:
undetectable		 1cbrB-5b3vB:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU B 124
LEU B 125
VAL B  98
SER B 308
VAL B 291
 None
 1.33A 1ie9A-5b3vB:
undetectable		 1ie9A-5b3vB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU B 192
PHE B 193
THR B 256
LEU B 257
 None
 1.01A 2eikA-5b3vB:
undetectable
2eikJ-5b3vB:
undetectable		 2eikA-5b3vB:
19.96
2eikJ-5b3vB:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 LEU B 114
ILE B  77
ILE B  87
ALA B  86
 None
 0.89A 2i30A-5b3vB:
undetectable		 2i30A-5b3vB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 TRP B  63
ALA B  91
LEU B  83
ALA B  90
 None
 1.03A 2jstA-5b3vB:
undetectable
2jstB-5b3vB:
undetectable		 2jstA-5b3vB:
12.17
2jstB-5b3vB:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 233
ALA B 231
LEU B 250
LEU B 192
SER B 187
 None
 1.20A 2oipC-5b3vB:
undetectable		 2oipC-5b3vB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE B  51
SER B  39
VAL B  13
VAL B  57
 None
 1.25A 3n61A-5b3vB:
undetectable
3n61B-5b3vB:
undetectable		 3n61A-5b3vB:
19.91
3n61B-5b3vB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 HIS B 172
HIS B 171
GLU B 212
PRO B 211
 None
 1.39A 4apjA-5b3vB:
undetectable
4apjP-5b3vB:
undetectable		 4apjA-5b3vB:
19.19
4apjP-5b3vB:
1.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY B  14
THR B  18
ASP B  73
VAL B  38
GLN B  36
 None
NAP  B 401 (-3.5A)
None
None
None
 1.38A 4df3A-5b3vB:
7.0		 4df3A-5b3vB:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY B  14
THR B  18
ASP B  73
VAL B  38
GLN B  36
 None
NAP  B 401 (-3.5A)
None
None
None
 1.40A 4df3B-5b3vB:
7.0		 4df3B-5b3vB:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLY B 264
THR B 263
GLY B 228
LEU B 144
 None
 0.91A 5jlcA-5b3vB:
undetectable		 5jlcA-5b3vB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 LEU B 257
ARG B 265
ILE B 275
PHE B 259
 None
 1.25A 5kirB-5b3vB:
undetectable		 5kirB-5b3vB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU B  37
PHE B  40
ALA B  21
ALA B  22
GLY B  19
 None
None
NAP  B 401 (-3.5A)
None
NAP  B 401 (-3.1A)
 1.11A 5tzoB-5b3vB:
undetectable		 5tzoB-5b3vB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLU B 262
GLY B 135
GLY B 278
GLU B 101
GLN B 286
 None
 0.87A 6gngB-5b3vB:
3.9		 6gngB-5b3vB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5b3v BILIVERDIN REDUCTASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 HIS B 129
ARG B  25
GLU B 128
ASP B 287
 None
None
NAP  B 401 (-3.4A)
None
 1.15A 6mn4D-5b3vB:
undetectable		 6mn4D-5b3vB:
24.04