SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 569
VAL A 613
LEU A 533
LEU A 529
 None
 0.85A 1cqpA-5b48A:
undetectable
1cqpB-5b48A:
undetectable		 1cqpA-5b48A:
15.37
1cqpB-5b48A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ALA A  25
LEU A 186
VAL A  70
ILE A  68
LEU A  52
 None
 1.01A 1fm6U-5b48A:
undetectable		 1fm6U-5b48A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		3 / 3 ILE A 364
ASP A 359
PHE A 320
 None
 0.50A 1uwjB-5b48A:
undetectable		 1uwjB-5b48A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 8 LYS B 125
GLY B 122
TYR B 121
THR B 131
 None
TDN  B 402 (-3.5A)
TDN  B 402 (-4.4A)
None
 1.02A 2aouA-5b48B:
2.6		 2aouA-5b48B:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 8 THR B  35
VAL B  38
VAL B  40
ALA B  27
 None
 1.08A 2ij7C-5b48B:
undetectable		 2ij7C-5b48B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 519
THR A 521
LEU A 529
VAL A 613
LEU A 594
 None
 1.08A 2qo5A-5b48A:
undetectable		 2qo5A-5b48A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 5 ARG A 506
ASP A 498
GLU A 503
LYS A 553
 None
 1.40A 2xrzA-5b48A:
undetectable
2xrzB-5b48A:
undetectable		 2xrzA-5b48A:
21.62
2xrzB-5b48A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 8 TYR A  90
VAL A  94
SER A 134
VAL A  77
 None
 1.27A 2y05A-5b48A:
undetectable
2y05B-5b48A:
undetectable		 2y05A-5b48A:
19.58
2y05B-5b48A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 HIS B  52
PHE B  53
GLN B  25
LEU B  21
 None
 1.09A 3bgdA-5b48B:
3.2		 3bgdA-5b48B:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 9 ILE A 403
GLY A 367
PRO A 401
VAL A 337
ILE A 339
 None
 1.01A 3nu4A-5b48A:
undetectable		 3nu4A-5b48A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 11 ILE B 252
ILE B 153
PHE B 255
ILE B 250
THR B 131
 None
 1.01A 3tmzA-5b48B:
undetectable		 3tmzA-5b48B:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 9 ILE A 509
LEU A 543
ILE A 520
ILE A 519
ILE A 566
 None
 1.07A 3zosA-5b48A:
undetectable		 3zosA-5b48A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A 455
ALA A 304
ILE A 298
VAL A 337
ILE A 339
 None
 1.03A 4aztA-5b48A:
3.2		 4aztA-5b48A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		3 / 3 LYS B 212
ARG B 212
TRP B 208
 None
 1.08A 4i90A-5b48B:
1.4		 4i90A-5b48B:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ILE B  20
ASP B 171
ASP B 217
GLY B 253
ILE B 252
 None
 1.08A 4o1eA-5b48B:
2.4		 4o1eA-5b48B:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 THR A 340
VAL A 338
THR A 236
HIS A 404
TYR A 342
 None
 1.23A 4s0vA-5b48A:
3.6		 4s0vA-5b48A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A 455
ALA A 304
ILE A 298
VAL A 337
ILE A 339
 None
 0.85A 4uw0A-5b48A:
2.8		 4uw0A-5b48A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 317
TYR A 253
ILE A 343
SER A 358
GLN A 576
 None
TDN  B 402 (-4.5A)
None
None
None
 1.05A 4xudA-5b48A:
undetectable		 4xudA-5b48A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 ASP A 387
PRO A 336
THR A 400
VAL A 402
 None
 1.06A 4yoaA-5b48A:
undetectable		 4yoaA-5b48A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		3 / 3 ARG A 354
TYR A  49
GLU A  38
 None
 0.62A 4zzbE-5b48A:
undetectable		 4zzbE-5b48A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 ILE B  58
PHE B  53
ILE B  85
GLU B  24
 None
 1.26A 4zzcA-5b48B:
undetectable
4zzcB-5b48B:
undetectable		 4zzcA-5b48B:
22.99
4zzcB-5b48B:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 ILE B  58
PHE B  53
ILE B  85
GLU B  24
 None
 1.31A 4zzcB-5b48B:
undetectable
4zzcC-5b48B:
undetectable		 4zzcB-5b48B:
22.99
4zzcC-5b48B:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 5 ARG A   2
ARG A 603
ILE A 532
GLU A 607
 None
 1.35A 4zzcC-5b48A:
0.0
4zzcD-5b48A:
0.0		 4zzcC-5b48A:
21.28
4zzcD-5b48A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE401_0
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 5 ARG A 603
ILE A 532
GLU A 607
ARG A   2
 None
 1.29A 4zzcA-5b48A:
0.0
4zzcE-5b48A:
0.0		 4zzcA-5b48A:
21.28
4zzcE-5b48A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 8 SER A 413
TYR A  34
ALA A 377
GLY A 379
 None
 0.92A 5albL-5b48A:
undetectable		 5albL-5b48A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 8 VAL B  29
ILE B  28
ILE B 114
PHE B  53
 None
 0.83A 5hw8H-5b48B:
undetectable		 5hw8H-5b48B:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A  59
THR A 355
GLN A 357
GLY A 379
LEU A 410
 None
 1.35A 5m50B-5b48A:
3.3		 5m50B-5b48A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A 187
ILE A 190
THR A 173
ILE A 172
 None
 0.86A 5murB-5b48A:
undetectable		 5murB-5b48A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 10 TYR A 211
ILE A 187
ILE A 190
THR A 173
ILE A 172
 None
 1.43A 5mvnD-5b48A:
undetectable		 5mvnD-5b48A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ILE B  69
VAL B  39
TYR B 161
ALA B 104
VAL B 109
 None
 1.14A 5n0rA-5b48B:
undetectable		 5n0rA-5b48B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ILE B  69
VAL B  39
TYR B 161
ALA B 104
VAL B 109
 None
 1.13A 5n0sB-5b48B:
undetectable		 5n0sB-5b48B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 ILE B  69
VAL B  39
TYR B 161
ALA B 104
VAL B 109
 None
 1.14A 5n0wA-5b48B:
1.9		 5n0wA-5b48B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.21A 5x7pA-5b48A:
undetectable		 5x7pA-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.25A 5x7pB-5b48A:
undetectable		 5x7pB-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.21A 5x7qA-5b48A:
undetectable		 5x7qA-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.25A 5x7qB-5b48A:
undetectable		 5x7qB-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.21A 5x7rA-5b48A:
undetectable		 5x7rA-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.23A 5x7rB-5b48A:
undetectable		 5x7rB-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 102
LEU A  88
LEU A  69
LEU A 130
LEU A 117
 None
 1.09A 6ew0B-5b48A:
undetectable		 6ew0B-5b48A:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 102
LEU A  88
LEU A  69
LEU A 130
LEU A 117
 None
 1.08A 6ew0D-5b48A:
undetectable		 6ew0D-5b48A:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 102
LEU A  88
LEU A  69
LEU A 130
LEU A 117
 None
 1.08A 6ew0H-5b48A:
undetectable		 6ew0H-5b48A:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 102
LEU A  88
LEU A  69
LEU A 130
LEU A 117
 None
 1.08A 6ew0I-5b48A:
undetectable		 6ew0I-5b48A:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
(Sulfurisphaera
tokodaii) 		4 / 6 SER A  71
ALA A  74
THR A  97
ALA A  93
 None
 1.17A 6ma6A-5b48A:
undetectable		 6ma6A-5b48A:
8.29