SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 5b4n F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 4 VAL A 294
TRP A 209
TRP A 295
 None
 1.45A 1gmkC-5b4nA:
undetectable
1gmkD-5b4nA:
undetectable		 1gmkC-5b4nA:
4.43
1gmkD-5b4nA:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5b4n F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 8 ASP A 208
PHE A 271
LEU A 128
TRP A 140
 None
 1.02A 1rmtD-5b4nA:
undetectable		 1rmtD-5b4nA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5b4n F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 222
LEU A 137
GLY A 133
LEU A 128
 None
 0.79A 6eu9D-5b4nA:
undetectable		 6eu9D-5b4nA:
18.32