SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 10 GLY A  92
PHE A  95
LEU A 214
THR A 341
LEU A 337
 None
 1.15A 1a8uA-5b58A:
undetectable		 1a8uA-5b58A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 10 GLY A  92
PHE A  95
LEU A 214
THR A 341
LEU A 337
 None
 1.21A 1a8uB-5b58A:
undetectable		 1a8uB-5b58A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 171
ALA A 165
LEU A 164
ARG A 163
PHE A 151
 None
 1.28A 1mx8A-5b58A:
undetectable		 1mx8A-5b58A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		4 / 5 ARG A  84
LEU A 340
ASP A 323
LEU A 324
 None
 1.19A 1n13B-5b58A:
undetectable
1n13C-5b58A:
undetectable		 1n13B-5b58A:
13.76
1n13C-5b58A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ALA A 182
ILE A 181
VAL A 161
ALA A 158
LEU A 268
 None
 1.13A 1udtA-5b58A:
undetectable		 1udtA-5b58A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		6 / 12 ALA A 182
ILE A 181
ILE A 183
VAL A 161
ALA A 158
LEU A 268
 None
 1.29A 1uduB-5b58A:
undetectable		 1uduB-5b58A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 10 ALA A 182
ILE A 181
VAL A 161
ALA A 158
LEU A 268
 None
 1.17A 1xp0A-5b58A:
undetectable		 1xp0A-5b58A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		4 / 8 THR A 319
GLY A 289
ASP A 112
ILE A 285
 None
 0.88A 2f9wA-5b58A:
undetectable
2f9wB-5b58A:
undetectable		 2f9wA-5b58A:
28.83
2f9wB-5b58A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ASP A 112
GLY A 114
PHE A  95
GLY A  94
VAL A 229
 None
 0.92A 2fqyA-5b58A:
undetectable		 2fqyA-5b58A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ALA A 182
ILE A 181
VAL A 161
ALA A 158
LEU A 268
 None
 0.93A 2h42B-5b58A:
undetectable		 2h42B-5b58A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 SER A 120
SER A 119
LEU A 176
LEU A 268
LEU A 105
 None
 1.06A 2xn5A-5b58A:
undetectable		 2xn5A-5b58A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 344
GLY A 289
GLN A 103
ARG A 297
THR A 319
 None
 1.19A 2yhdA-5b58A:
undetectable		 2yhdA-5b58A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 344
LEU A 290
GLY A 289
GLN A 103
THR A 319
 None
 1.40A 2yhdA-5b58A:
undetectable		 2yhdA-5b58A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 VAL A  91
GLY A  92
GLY A  96
THR A 319
LEU A 337
 None
 0.94A 3dh0A-5b58A:
undetectable		 3dh0A-5b58A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 GLY A  94
VAL A 275
ALA A 316
GLY A 315
ILE A 285
 None
 1.11A 3ku1G-5b58A:
undetectable		 3ku1G-5b58A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 236
GLY A  99
ALA A 100
GLY A 315
LEU A 308
 None
 0.89A 3ogqB-5b58A:
undetectable		 3ogqB-5b58A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 VAL A 161
GLY A 180
ILE A 284
GLY A 114
ALA A 122
 None
 1.00A 3sufB-5b58A:
undetectable		 3sufB-5b58A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 ALA A 299
GLY A 310
PRO A 309
VAL A 307
 None
 0.86A 4dubA-5b58A:
1.8		 4dubA-5b58A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 GLY A 117
GLY A 114
ILE A 181
ILE A 183
SER A 120
 None
 1.11A 4iv0B-5b58A:
undetectable		 4iv0B-5b58A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 GLY A 117
GLY A 114
ILE A 181
ILE A 183
SER A 120
 None
 1.10A 4mwzA-5b58A:
undetectable		 4mwzA-5b58A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 GLY A 121
GLY A 154
LEU A 155
GLY A 117
VAL A 116
 None
 0.80A 4o33A-5b58A:
undetectable		 4o33A-5b58A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 THR A  98
GLN A 103
ALA A 316
GLY A 315
ALA A 311
 None
 1.09A 4qvvH-5b58A:
undetectable		 4qvvH-5b58A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 THR A  98
GLN A 103
ALA A 316
GLY A 315
ALA A 311
 None
 1.08A 4qvvV-5b58A:
undetectable		 4qvvV-5b58A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 THR A  98
GLN A 103
ALA A 316
GLY A 315
ALA A 311
 None
 1.08A 4qvyH-5b58A:
undetectable		 4qvyH-5b58A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 ALA A 101
THR A  98
ALA A 100
GLY A 232
GLY A 233
 None
 1.14A 4qwuK-5b58A:
undetectable
4qwuL-5b58A:
undetectable		 4qwuK-5b58A:
19.90
4qwuL-5b58A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 ALA A 101
THR A  98
ALA A 100
GLY A 232
GLY A 233
 None
 1.11A 4qwuY-5b58A:
undetectable
4qwuZ-5b58A:
undetectable		 4qwuY-5b58A:
19.90
4qwuZ-5b58A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 GLY A 289
GLY A  96
ALA A 100
ALA A 111
LEU A 290
 None
 1.07A 5bw4B-5b58A:
undetectable		 5bw4B-5b58A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ALA A 311
GLY A 289
GLY A  96
GLY A  92
LEU A 290
 None
 0.93A 5c0oH-5b58A:
undetectable		 5c0oH-5b58A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5b58 PUTATIVE HEMIN ABC
TRANSPORT SYSTEM,
MEMBRANE PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 THR A  98
GLN A 103
ALA A 316
GLY A 315
ALA A 311
 None
 1.06A 5d0xV-5b58A:
undetectable		 5d0xV-5b58A:
20.82