SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		5 / 11 LEU B 242
ALA B 212
VAL B 281
LEU B 288
LEU B 315
 None
 1.14A 1rlbF-5b5qB:
undetectable		 1rlbF-5b5qB:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		3 / 3 ALA B 165
VAL B 163
TRP B 348
 None
 0.87A 1tkqA-5b5qB:
undetectable		 1tkqA-5b5qB:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		5 / 12 LEU B 188
ALA B 194
VAL B 279
ILE B 204
VAL B 244
 None
 1.12A 3gguA-5b5qB:
undetectable		 3gguA-5b5qB:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		5 / 10 LEU B 188
ALA B 194
VAL B 279
ILE B 204
VAL B 244
 None
 1.07A 3nu9B-5b5qB:
undetectable		 3nu9B-5b5qB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		4 / 5 LEU B 255
ALA B 194
MET B 262
THR B 258
 None
 1.20A 3vasB-5b5qB:
undetectable		 3vasB-5b5qB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		4 / 5 HIS B 275
GLN B 338
SER B 343
VAL B 271
 None
 1.30A 4a99D-5b5qB:
undetectable		 4a99D-5b5qB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5b5q MEMBRANE THIOL
PROTEASE
(Chlamydia
trachomatis) 		4 / 7 ALA B 194
ASP B 209
ILE B 206
ILE B 186
 None
 0.78A 6fbnA-5b5qB:
undetectable		 6fbnA-5b5qB:
19.85