SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 8 CYH A  46
ASP A  48
HIS A 102
CYH A 126
GLY A 127
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 0.30A 1ekjA-5b5zA:
10.4
1ekjB-5b5zA:
10.5		 1ekjA-5b5zA:
21.28
1ekjB-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 8 CYH A  46
ASP A  48
HIS A 102
CYH A 126
GLY A 127
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 0.36A 1ekjA-5b5zA:
10.4
1ekjB-5b5zA:
10.8		 1ekjA-5b5zA:
21.28
1ekjB-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 7 CYH A  46
ASP A  48
HIS A 102
GLY A 127
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
None
 0.37A 1ekjE-5b5zA:
10.4
1ekjF-5b5zA:
10.3		 1ekjE-5b5zA:
21.28
1ekjF-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 8 CYH A  46
ASP A  48
HIS A 102
CYH A 126
GLY A 127
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 0.29A 1ekjG-5b5zA:
10.4
1ekjH-5b5zA:
10.3		 1ekjG-5b5zA:
21.28
1ekjH-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 8 CYH A  46
HIS A 102
CYH A 126
GLY A 127
 ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 0.92A 1ekjG-5b5zA:
10.4
1ekjH-5b5zA:
10.3		 1ekjG-5b5zA:
21.28
1ekjH-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 6 CYH A  46
ASP A  48
HIS A 102
CYH A 126
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
 0.31A 1ekjG-5b5zA:
10.5
1ekjH-5b5zA:
10.3		 1ekjG-5b5zA:
21.28
1ekjH-5b5zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 GLY A  73
TYR A  99
CYH A 126
ALA A  72
ALA A 129
 None
None
ZN  A 500 (-2.3A)
None
None
 1.16A 2bm9A-5b5zA:
3.8		 2bm9A-5b5zA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 GLY A  73
TYR A  99
CYH A 126
ALA A  72
ALA A 129
 None
None
ZN  A 500 (-2.3A)
None
None
 1.12A 2br4B-5b5zA:
3.9		 2br4B-5b5zA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 GLY A  73
TYR A  99
CYH A 126
ALA A  72
ALA A 129
 None
None
ZN  A 500 (-2.3A)
None
None
 1.15A 2br4D-5b5zA:
2.3		 2br4D-5b5zA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		3 / 3 CYH A  46
CYH A 126
HIS A 102
 ZN  A 500 (-2.2A)
ZN  A 500 (-2.3A)
ZN  A 500 (-3.3A)
 0.87A 2iwkA-5b5zA:
undetectable		 2iwkA-5b5zA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 8 VAL A 194
PRO A 197
VAL A 198
SER A 199
 None
 0.70A 2v32C-5b5zA:
undetectable
2v32D-5b5zA:
undetectable		 2v32C-5b5zA:
21.95
2v32D-5b5zA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 10 PHE A  74
ALA A  72
ALA A 129
LEU A 186
VAL A 136
 None
 1.12A 2wuzA-5b5zA:
undetectable		 2wuzA-5b5zA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 10 PHE A  74
ALA A  72
ALA A 129
LEU A 186
VAL A 136
 None
 1.10A 2wuzB-5b5zA:
undetectable		 2wuzB-5b5zA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.29A 2yldA-5b5zA:
undetectable		 2yldA-5b5zA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.21A 2ylgA-5b5zA:
undetectable		 2ylgA-5b5zA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		3 / 3 CYH A  46
CYH A 126
HIS A 102
 ZN  A 500 (-2.2A)
ZN  A 500 (-2.3A)
ZN  A 500 (-3.3A)
 0.87A 3dtuB-5b5zA:
undetectable		 3dtuB-5b5zA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		3 / 3 CYH A  46
CYH A 126
HIS A 102
 ZN  A 500 (-2.2A)
ZN  A 500 (-2.3A)
ZN  A 500 (-3.3A)
 0.86A 3dtuD-5b5zA:
undetectable		 3dtuD-5b5zA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 8 PHE A  74
ALA A  72
ALA A 129
LEU A 186
 None
 0.90A 3khmA-5b5zA:
undetectable		 3khmA-5b5zA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 8 PHE A  74
ALA A  72
ALA A 129
LEU A 186
 None
 0.81A 3l4dD-5b5zA:
undetectable		 3l4dD-5b5zA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		6 / 10 ASP A  48
HIS A 102
CYH A 126
GLY A 127
ALA A 129
ALA A 131
 ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
None
None
 1.33A 3ucjA-5b5zA:
12.0		 3ucjA-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 10 CYH A  46
ASP A  48
HIS A 102
CYH A 126
ALA A 132
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 1.01A 3ucjA-5b5zA:
12.0		 3ucjA-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		6 / 10 CYH A  46
ASP A  48
HIS A 102
CYH A 126
GLY A 127
ALA A 131
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
None
 0.36A 3ucjA-5b5zA:
12.0		 3ucjA-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		6 / 10 ASP A  48
HIS A 102
CYH A 126
GLY A 127
ALA A 129
ALA A 131
 ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
None
None
 1.31A 3ucjB-5b5zA:
12.3		 3ucjB-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 10 CYH A  46
ASP A  48
HIS A 102
CYH A 126
ALA A 132
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
 1.01A 3ucjB-5b5zA:
12.3		 3ucjB-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		6 / 10 CYH A  46
ASP A  48
HIS A 102
CYH A 126
GLY A 127
ALA A 131
 ZN  A 500 (-2.2A)
ZN  A 500 ( 4.8A)
ZN  A 500 (-3.3A)
ZN  A 500 (-2.3A)
None
None
 0.37A 3ucjB-5b5zA:
12.3		 3ucjB-5b5zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 6 THR A  39
ASN A  38
GLY A  92
ILE A 219
 None
 0.82A 3w9tF-5b5zA:
undetectable		 3w9tF-5b5zA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.29A 3zwiA-5b5zA:
undetectable		 3zwiA-5b5zA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 GLY A 112
ALA A 124
LEU A 196
VAL A 103
ILE A 233
 None
 1.03A 4aztA-5b5zA:
3.0		 4aztA-5b5zA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 LEU A 179
ASP A  48
GLY A 127
GLY A 123
GLY A  73
 None
ZN  A 500 ( 4.8A)
None
None
None
 1.14A 4blvA-5b5zA:
2.9		 4blvA-5b5zA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 ALA A  23
SER A  26
VAL A  25
GLN A 232
ILE A  98
 None
 1.24A 4c49A-5b5zA:
undetectable		 4c49A-5b5zA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 4 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.29A 4cipA-5b5zA:
undetectable		 4cipA-5b5zA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		3 / 3 LEU A  97
ILE A 225
ARG A 251
 None
 0.63A 4mk4B-5b5zA:
undetectable		 4mk4B-5b5zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 GLY A 112
ALA A 124
LEU A 196
VAL A 103
ILE A 233
 None
 1.08A 4uw0A-5b5zA:
2.4		 4uw0A-5b5zA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		3 / 3 LYS A   9
ARG A 246
VAL A 245
 None
 0.63A 4x3uA-5b5zA:
undetectable
4x3uB-5b5zA:
undetectable		 4x3uA-5b5zA:
11.03
4x3uB-5b5zA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 8 THR A 195
LEU A 196
THR A 185
LEU A 186
 None
 0.73A 4z90F-5b5zA:
undetectable
4z90G-5b5zA:
undetectable
4z90H-5b5zA:
undetectable
4z90I-5b5zA:
undetectable
4z90J-5b5zA:
undetectable		 4z90F-5b5zA:
19.94
4z90G-5b5zA:
19.94
4z90H-5b5zA:
19.94
4z90I-5b5zA:
19.94
4z90J-5b5zA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.22A 5jliA-5b5zA:
undetectable		 5jliA-5b5zA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 4 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.27A 5jslA-5b5zA:
undetectable		 5jslA-5b5zA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 ALA A 129
GLY A  70
CYH A  46
HIS A 102
 None
None
ZN  A 500 (-2.2A)
ZN  A 500 (-3.3A)
 1.23A 5jt4A-5b5zA:
undetectable		 5jt4A-5b5zA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 5 LEU A 196
VAL A 200
CYH A 125
CYH A  46
 None
None
None
ZN  A 500 (-2.2A)
 1.35A 5te0A-5b5zA:
undetectable		 5te0A-5b5zA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		5 / 12 PHE A 248
GLY A 229
LEU A  54
ILE A 231
LEU A  29
 None
 1.22A 5y2tA-5b5zA:
undetectable		 5y2tA-5b5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5b5z PTLCIB4 H88A MUTANT
(Phaeodactylum
tricornutum) 		4 / 4 MET A  85
GLY A  83
HIS A 218
GLY A  87
 None
 1.41A 6fgdA-5b5zA:
undetectable		 6fgdA-5b5zA:
21.35