SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 141
PRO B 171
THR B 140
PRO B 142
 None
 1.31A 1dsdC-5b6fB:
undetectable		 1dsdC-5b6fB:
3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 141
PRO B 171
THR B 140
PRO B 142
 None
 1.31A 1dsdC-5b6fB:
undetectable		 1dsdC-5b6fB:
3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL B 187
VAL B 205
SER B 203
ASN B 220
ASN B 179
 None
 1.43A 3nyaA-5b6fB:
undetectable		 3nyaA-5b6fB:
19.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		5 / 12 ALA B  43
MET B  53
ARG B  93
ASN B  98
VAL B 100
 None
 0.57A 3qxtA-5b6fB:
19.3		 3qxtA-5b6fB:
36.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL B  21
ALA B  43
MET B  53
ARG B  93
VAL B 100
 None
 0.74A 3qxvB-5b6fB:
19.3		 3qxvB-5b6fB:
35.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		5 / 11 VAL B  21
ALA B  43
MET B  53
ARG B  93
VAL B 100
 None
 0.80A 3qxvC-5b6fB:
19.5		 3qxvC-5b6fB:
35.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR B 115
ASP B  65
ASP B 111
 None
 0.85A 5x6yA-5b6fB:
undetectable		 5x6yA-5b6fB:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR B  81
GLY B  87
THR B  90
 None
 0.14A 6cjkB-5b6fB:
25.2		 6cjkB-5b6fB:
31.22