SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b6k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		5 / 12 TYR A 208
ILE A 172
THR A 139
PHE A 145
LEU A 314
 None
 1.10A 2mjiA-5b6kA:
undetectable		 2mjiA-5b6kA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 6 ASP A 339
TYR A 338
PHE A 210
LEU A 285
 None
 1.23A 2w98A-5b6kA:
6.5
2w98B-5b6kA:
6.5		 2w98A-5b6kA:
22.91
2w98B-5b6kA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 7 TYR A 190
VAL A  12
VAL A 126
ILE A 114
 None
 0.84A 3ms9B-5b6kA:
undetectable		 3ms9B-5b6kA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 7 TYR A 190
VAL A  12
VAL A 126
ILE A 114
 None
 0.86A 3mssB-5b6kA:
undetectable		 3mssB-5b6kA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 6 TYR A 190
VAL A  12
VAL A 126
ILE A 114
 None
 0.81A 3pyyA-5b6kA:
undetectable		 3pyyA-5b6kA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 8 THR A 111
LEU A 115
VAL A 129
VAL A 131
 None
 0.90A 4em2A-5b6kA:
undetectable		 4em2A-5b6kA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 5 ASP A 336
VAL A 207
PHE A 280
GLY A 278
 None
 1.22A 4xp6A-5b6kA:
undetectable		 4xp6A-5b6kA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 5 HIS A  22
GLN A  21
ILE A  51
TYR A 215
 None
 1.24A 5fuqA-5b6kA:
5.3
5fuqB-5b6kA:
undetectable		 5fuqA-5b6kA:
21.64
5fuqB-5b6kA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 6 VAL A 207
SER A 134
ARG A 272
ILE A 204
 None
 1.08A 5jw1B-5b6kA:
undetectable		 5jw1B-5b6kA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		5 / 12 ASP A 339
ILE A 250
ASP A 251
ARG A 253
PHE A  18
 None
 1.41A 5nn8A-5b6kA:
undetectable		 5nn8A-5b6kA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		5 / 12 MET A 144
ALA A 246
TYR A 175
VAL A 229
PHE A 210
 None
 1.40A 5vlmH-5b6kA:
undetectable		 5vlmH-5b6kA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 6 HIS A  46
ASN A 214
VAL A 216
GLN A 343
 None
 1.29A 5xdhA-5b6kA:
undetectable
5xdhC-5b6kA:
undetectable		 5xdhA-5b6kA:
11.97
5xdhC-5b6kA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 6 GLN A 343
HIS A  46
ASN A 214
VAL A 216
 None
 1.34A 5xdhA-5b6kA:
undetectable
5xdhC-5b6kA:
undetectable		 5xdhA-5b6kA:
11.97
5xdhC-5b6kA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		3 / 3 VAL A 216
TYR A 215
GLU A 346
 None
 0.93A 5zmqD-5b6kA:
undetectable
5zmqE-5b6kA:
undetectable		 5zmqD-5b6kA:
19.62
5zmqE-5b6kA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		5 / 9 TYR A 208
VAL A 207
PHE A 135
LEU A 314
ILE A 154
 None
 1.16A 5zsfA-5b6kA:
0.8
5zsfB-5b6kA:
1.7		 5zsfA-5b6kA:
13.64
5zsfB-5b6kA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 5b6k UNCHARACTERIZED
PROTEIN CGKR1
([Candida]
glabrata) 		4 / 4 VAL A 252
GLY A 211
ASP A 336
ASP A 339
 None
 1.47A 6cjkC-5b6kA:
undetectable		 6cjkC-5b6kA:
19.13