SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.01A 1t85A-5b71B:
undetectable		 1t85A-5b71B:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.99A 1t87A-5b71B:
undetectable		 1t87A-5b71B:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5b71 COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ILE E  87
ALA E  35
PHE E  31
ILE E  39
LEU E 104
 None
 0.86A 1tdrA-5b71E:
undetectable		 1tdrA-5b71E:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.02A 1yrdA-5b71B:
undetectable		 1yrdA-5b71B:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.02A 2feuB-5b71B:
undetectable		 2feuB-5b71B:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5b71 COMPLEMENT C5 BETA
CHAIN
SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 VAL E  43
TYR E  46
HIS B 108
PHE E  50
SER B  56
 None
 1.34A 2gl0A-5b71E:
undetectable
2gl0C-5b71E:
undetectable		 2gl0A-5b71E:
21.30
2gl0C-5b71E:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.99A 2zwtA-5b71B:
undetectable		 2zwtA-5b71B:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.02A 2zwuA-5b71B:
undetectable		 2zwuA-5b71B:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.02A 3fwjA-5b71B:
undetectable		 3fwjA-5b71B:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 THR B 120
GLU B 158
HIS B 210
 None
 0.67A 3g1uB-5b71B:
undetectable		 3g1uB-5b71B:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_B_TESB226_1
(IMMUNOGLOBULIN LIGHT
CHAIN
IMMUNOGLOBULIN HEAVY
CHAIN)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 9 TRP B  48
ALA B  51
TYR B  60
ASP B 100
MET B 110
 None
 1.23A 3kdmA-5b71B:
14.8
3kdmB-5b71B:
20.5		 3kdmA-5b71B:
30.67
3kdmB-5b71B:
76.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_H_TESH226_1
(IMMUNOGLOBULIN HEAVY
CHAIN
IMMUNOGLOBULIN LIGHT
CHAIN)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 9 TRP B  48
ALA B  51
TYR B  60
ASP B 100
MET B 110
 None
 1.28A 3kdmH-5b71B:
23.1
3kdmL-5b71B:
14.5		 3kdmH-5b71B:
76.55
3kdmL-5b71B:
30.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5b71 SKY59 FAB HEAVY
CHAIN
COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		3 / 3 HIS B  30
SER E 112
GLU E 105
 None
 0.67A 3s8pA-5b71B:
undetectable		 3s8pA-5b71B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.97A 3wrhA-5b71B:
undetectable		 3wrhA-5b71B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.99A 3wrjA-5b71B:
undetectable		 3wrjA-5b71B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 1.00A 3wrlA-5b71B:
undetectable		 3wrlA-5b71B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.99A 3wrmA-5b71B:
undetectable		 3wrmA-5b71B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 TYR B  33
THR B  28
VAL B   2
ASP B 104
 None
 0.93A 4l4gA-5b71B:
undetectable		 4l4gA-5b71B:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5b71 COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ALA E  35
PHE E  31
ILE E  39
LEU E 104
ILE E  56
 None
 1.12A 4nx7A-5b71E:
undetectable		 4nx7A-5b71E:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5b71 COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ILE E  87
ALA E  35
ILE E  39
LEU E 104
ILE E  56
 None
 1.04A 4p3qA-5b71E:
undetectable		 4p3qA-5b71E:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5b71 COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ILE E  87
ALA E  35
ILE E  39
LEU E 104
ILE E  56
 None
 1.06A 4pthA-5b71E:
undetectable		 4pthA-5b71E:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5b71 SKY59 FAB HEAVY
CHAIN
COMPLEMENT C5 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ALA B  24
HIS E  70
THR E  53
GLY B  55
SER B  56
 None
 1.17A 5hfjB-5b71B:
undetectable		 5hfjB-5b71B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5b71 SKY59 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 VAL B  49
LEU B  82
LEU B  20
MET B  87
 None
 1.07A 6f6sA-5b71B:
undetectable
6f6sB-5b71B:
undetectable		 6f6sA-5b71B:
15.25
6f6sB-5b71B:
17.41