SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 LEU A  66
LEU A  48
ALA A  47
ILE A 117
ILE A  33
 None
 1.03A 1crbA-5b7nA:
undetectable		 1crbA-5b7nA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.00A 1gtnM-5b7nA:
undetectable
1gtnN-5b7nA:
undetectable		 1gtnM-5b7nA:
15.74
1gtnN-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.04A 1gtnO-5b7nA:
undetectable
1gtnP-5b7nA:
undetectable		 1gtnO-5b7nA:
15.74
1gtnP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.02A 1gtnU-5b7nA:
undetectable
1gtnV-5b7nA:
undetectable		 1gtnU-5b7nA:
15.74
1gtnV-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 ALA A 217
GLY A 115
ALA A 105
THR A 245
HIS A 248
 None
 0.99A 1gtnL-5b7nA:
undetectable
1gtnV-5b7nA:
undetectable		 1gtnL-5b7nA:
15.74
1gtnV-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 12 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.40A 1jdvE-5b7nA:
23.1
1jdvF-5b7nA:
22.4		 1jdvE-5b7nA:
25.09
1jdvF-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.32A 1odiA-5b7nA:
17.1		 1odiA-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.34A 1odiB-5b7nA:
23.6		 1odiB-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.33A 1odiC-5b7nA:
24.2		 1odiC-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.36A 1odiD-5b7nA:
24.3		 1odiD-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.32A 1odiE-5b7nA:
24.3		 1odiE-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		7 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
SAH  A 301 (-3.2A)
 0.35A 1odiF-5b7nA:
23.4		 1odiF-5b7nA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 9 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.46A 1pk7A-5b7nA:
23.4		 1pk7A-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.30A 1pk7C-5b7nA:
24.2		 1pk7C-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.35A 1pk9A-5b7nA:
23.4		 1pk9A-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 9 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.38A 1pk9B-5b7nA:
23.5		 1pk9B-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.25A 1pk9C-5b7nA:
24.0		 1pk9C-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.40A 1pw7A-5b7nA:
23.4		 1pw7A-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 1utdL-5b7nA:
undetectable
1utdM-5b7nA:
undetectable		 1utdL-5b7nA:
15.74
1utdM-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.00A 1utdO-5b7nA:
undetectable
1utdP-5b7nA:
undetectable		 1utdO-5b7nA:
15.74
1utdP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.02A 1utdP-5b7nA:
undetectable
1utdQ-5b7nA:
undetectable		 1utdP-5b7nA:
15.74
1utdQ-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 1utdT-5b7nA:
undetectable
1utdU-5b7nA:
undetectable		 1utdT-5b7nA:
15.74
1utdU-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 10 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.49A 1z35A-5b7nA:
23.6		 1z35A-5b7nA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 9 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.36A 1z37A-5b7nA:
23.6		 1z37A-5b7nA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
 0.33A 2ac7A-5b7nA:
23.1
2ac7B-5b7nA:
23.1		 2ac7A-5b7nA:
26.02
2ac7B-5b7nA:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
 0.33A 2ac7A-5b7nA:
23.1
2ac7B-5b7nA:
23.1		 2ac7A-5b7nA:
26.02
2ac7B-5b7nA:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 ASN A 200
HIS A 108
GLY A 106
GLY A 127
ALA A 196
 None
None
SAH  A 301 (-3.2A)
None
None
 1.16A 3pp7B-5b7nA:
2.1		 3pp7B-5b7nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 ASN A 200
HIS A 108
GLY A 107
GLY A 127
ALA A 196
 None
 1.31A 3pp7B-5b7nA:
2.1		 3pp7B-5b7nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 11 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.34A 3uawA-5b7nA:
24.3		 3uawA-5b7nA:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 10 THR A 104
GLY A 106
GLU A 219
MET A 220
GLU A 221
ASN A 244
 SAH  A 301 (-4.3A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 (-3.2A)
 0.30A 3uayA-5b7nA:
24.0		 3uayA-5b7nA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.36A 4d9hA-5b7nA:
23.0		 4d9hA-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
ALA A 196
GLU A 219
MET A 220
GLU A 221
 SAH  A 301 (-3.2A)
None
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
 0.70A 4da7A-5b7nA:
23.1		 4da7A-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.45A 4da7A-5b7nA:
23.1		 4da7A-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 11 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.49A 4danA-5b7nA:
22.5		 4danA-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 GLY A 106
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.52A 4danA-5b7nA:
22.5
4danB-5b7nA:
22.1		 4danA-5b7nA:
25.09
4danB-5b7nA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		3 / 3 ASP A 116
ARG A 187
ASP A 109
 None
 0.66A 4fp9D-5b7nA:
undetectable		 4fp9D-5b7nA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		3 / 3 ASP A 116
ARG A 187
ASP A 109
 None
 0.81A 4fzvA-5b7nA:
undetectable		 4fzvA-5b7nA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		3 / 3 ARG A 240
GLU A 221
ASN A 101
 SAH  A 301 (-3.9A)
SAH  A 301 (-2.6A)
None
 0.78A 4imaD-5b7nA:
undetectable		 4imaD-5b7nA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		3 / 3 ARG A 240
GLU A 221
ASN A 101
 SAH  A 301 (-3.9A)
SAH  A 301 (-2.6A)
None
 0.83A 4ip7D-5b7nA:
undetectable		 4ip7D-5b7nA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 GLY A 107
GLY A 106
ASP A 246
ILE A 193
GLY A 191
 None
SAH  A 301 (-3.2A)
None
None
None
 0.95A 4obwB-5b7nA:
undetectable		 4obwB-5b7nA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		4 / 7 LEU A  80
THR A  87
ALA A  83
THR A  76
 None
 0.96A 5bojB-5b7nA:
undetectable		 5bojB-5b7nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 ALA A 217
GLY A 115
ALA A 105
THR A 245
HIS A 248
 None
 1.01A 5eeuI-5b7nA:
undetectable
5eeuJ-5b7nA:
undetectable		 5eeuI-5b7nA:
15.74
5eeuJ-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.02A 5eeuO-5b7nA:
undetectable
5eeuP-5b7nA:
undetectable		 5eeuO-5b7nA:
15.74
5eeuP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.05A 5eeuQ-5b7nA:
undetectable
5eeuR-5b7nA:
undetectable		 5eeuQ-5b7nA:
15.74
5eeuR-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 ALA A 217
GLY A 115
ALA A 105
THR A 245
HIS A 248
 None
 1.01A 5eevI-5b7nA:
undetectable
5eevJ-5b7nA:
undetectable		 5eevI-5b7nA:
15.74
5eevJ-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5eevO-5b7nA:
undetectable
5eevP-5b7nA:
undetectable		 5eevO-5b7nA:
15.74
5eevP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.05A 5eevQ-5b7nA:
undetectable
5eevR-5b7nA:
undetectable		 5eevQ-5b7nA:
15.74
5eevR-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 ALA A 217
GLY A 115
ALA A 105
THR A 245
HIS A 248
 None
 1.01A 5eewI-5b7nA:
undetectable
5eewJ-5b7nA:
undetectable		 5eewI-5b7nA:
15.74
5eewJ-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5eewO-5b7nA:
undetectable
5eewP-5b7nA:
undetectable		 5eewO-5b7nA:
15.74
5eewP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.05A 5eewQ-5b7nA:
undetectable
5eewR-5b7nA:
undetectable		 5eewQ-5b7nA:
15.74
5eewR-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.02A 5eexO-5b7nA:
undetectable
5eexP-5b7nA:
undetectable		 5eexO-5b7nA:
15.74
5eexP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5eeyO-5b7nA:
undetectable
5eeyP-5b7nA:
undetectable		 5eeyO-5b7nA:
15.74
5eeyP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5eezO-5b7nA:
undetectable
5eezP-5b7nA:
undetectable		 5eezO-5b7nA:
15.74
5eezP-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5ef0O-5b7nA:
undetectable
5ef0P-5b7nA:
undetectable		 5ef0O-5b7nA:
15.74
5ef0P-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5ef1O-5b7nA:
undetectable
5ef1P-5b7nA:
undetectable		 5ef1O-5b7nA:
15.74
5ef1P-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5ef2O-5b7nA:
undetectable
5ef2P-5b7nA:
undetectable		 5ef2O-5b7nA:
15.74
5ef2P-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 115
ALA A 105
THR A 245
HIS A 248
ALA A 217
 None
 1.03A 5ef3O-5b7nA:
undetectable
5ef3P-5b7nA:
undetectable		 5ef3O-5b7nA:
15.74
5ef3P-5b7nA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 12 LEU A  66
LEU A  48
ALA A  47
ILE A 117
ILE A  33
 None
 1.08A 5h8tA-5b7nA:
undetectable		 5h8tA-5b7nA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		5 / 10 GLY A 106
ALA A 196
GLU A 219
MET A 220
GLU A 221
 SAH  A 301 (-3.2A)
None
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
 0.66A 5i3cB-5b7nA:
24.0		 5i3cB-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		6 / 11 GLY A 106
ALA A 196
GLU A 219
MET A 220
GLU A 221
SER A 243
 SAH  A 301 (-3.2A)
None
SAH  A 301 (-4.9A)
SAH  A 301 (-3.6A)
SAH  A 301 (-2.6A)
SAH  A 301 ( 4.0A)
 0.74A 5i3cC-5b7nA:
23.9		 5i3cC-5b7nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		4 / 8 ASN A 125
GLY A 127
ALA A 128
VAL A 150
 None
 0.42A 5kr1B-5b7nA:
undetectable		 5kr1B-5b7nA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		3 / 3 ASP A 116
ARG A 187
ASP A 109
 None
 0.87A 5zvgB-5b7nA:
undetectable		 5zvgB-5b7nA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 5b7n MTA/SAH NUCLEOSIDASE
(Aeromonas
hydrophila) 		4 / 7 LEU A 112
ALA A 217
ALA A 216
THR A 121
 None
 0.84A 6a7jA-5b7nA:
undetectable		 6a7jA-5b7nA:
17.20