SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		3 / 3 VAL A  96
LYS A  45
HIS A  13
 None
 0.95A 3elzA-5b7wA:
undetectable		 3elzA-5b7wA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		4 / 8 SER A   3
ASN A 158
PHE A 159
ASP A 161
 None
 1.30A 3n66B-5b7wA:
undetectable		 3n66B-5b7wA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		3 / 3 LYS A  33
SER A  53
GLN A  56
 None
 0.73A 3si7A-5b7wA:
undetectable		 3si7A-5b7wA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		4 / 8 LEU A  64
VAL A  94
VAL A  96
GLN A  98
 None
 0.90A 4em2A-5b7wA:
undetectable		 4em2A-5b7wA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		5 / 12 LEU A 154
ALA A 143
GLN A 139
ARG A 135
LEU A 112
 None
 1.41A 4udaA-5b7wA:
undetectable		 4udaA-5b7wA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5b7w UPF0234 PROTEIN
XC_3703
(Xanthomonas
campestris) 		5 / 9 LEU A 112
VAL A 119
VAL A 130
ILE A 142
ASP A 140
 None
 1.21A 5yf9X-5b7wA:
undetectable		 5yf9X-5b7wA:
18.71