SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1507_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5b82	TLL0287 PROTEIN (Thermosynechococ cus elongatus)	3 / 3	GLN A 88 HIS A 98 ARG A 94	HEC A 501 (-3.5A) HEC A 501 (-3.7A) HEC A 501 (-4.6A)	0.90A	1zlqA-5b82A: undetectable	1zlqA-5b82A: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_L_TRPL1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	5b82	TLL0287 PROTEIN (Thermosynechococ cus elongatus)	5 / 9	GLY A 83 GLN A 184 ILE A 78 VAL A 86 VAL A 178	None	1.48A	3fi0L-5b82A: undetectable	3fi0L-5b82A: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_R_TRPR1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	5b82	TLL0287 PROTEIN (Thermosynechococ cus elongatus)	5 / 9	GLY A 83 GLN A 184 ILE A 78 VAL A 86 VAL A 178	None	1.43A	3fi0R-5b82A: undetectable	3fi0R-5b82A: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_B_DVAB8_0 (GRAMICIDIN D)	5b82	TLL0287 PROTEIN (Thermosynechococ cus elongatus)	3 / 3	VAL A 178 VAL A 129 TRP A 84	None	0.83A	3l8lA-5b82A: undetectable 3l8lB-5b82A: undetectable	3l8lA-5b82A: 6.61 3l8lB-5b82A: 6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JLT_A_8PRA505_1 (CYTOCHROME P450 2B4)	5b82	TLL0287 PROTEIN (Thermosynechococ cus elongatus)	4 / 8	ILE A 78 ALA A 37 GLU A 39 VAL A 178	None	0.59A	4jltA-5b82A: undetectable	4jltA-5b82A: 18.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZLQ_A_ACTA1507_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5b82","TLL0287 PROTEIN","Thermosynechococcus elongatus",3,"GLN A  88;HIS A  98;ARG A  94","HEC A 501 (-3.5A);HEC A 501 (-3.7A);HEC A 501 (-4.6A)","0.90A","1zlqA-5b82A:undetectable","1zlqA-5b82A:18.73"],["3FI0_L_TRPL1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","5b82","TLL0287 PROTEIN","Thermosynechococcus elongatus",5,"GLY A  83;GLN A 184;ILE A  78;VAL A  86;VAL A 178","None","1.48A","3fi0L-5b82A:undetectable","3fi0L-5b82A:19.51"],["3FI0_R_TRPR1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","5b82","TLL0287 PROTEIN","Thermosynechococcus elongatus",5,"GLY A  83;GLN A 184;ILE A  78;VAL A  86;VAL A 178","None","1.43A","3fi0R-5b82A:undetectable","3fi0R-5b82A:19.51"],["3L8L_B_DVAB8_0","GRAMICIDIN D","5b82","TLL0287 PROTEIN","Thermosynechococcus elongatus",3,"VAL A 178;VAL A 129;TRP A  84","None","0.83A","3l8lA-5b82A:undetectable;3l8lB-5b82A:undetectable","3l8lA-5b82A:6.61;3l8lB-5b82A:6.61"],["4JLT_A_8PRA505_1","CYTOCHROME P450 2B4","5b82","TLL0287 PROTEIN","Thermosynechococcus elongatus",4,"ILE A  78;ALA A  37;GLU A  39;VAL A 178","None","0.59A","4jltA-5b82A:undetectable","4jltA-5b82A:18.61"]]