SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 12 ILE A  79
THR A  83
PHE A 121
LEU A 119
ILE A 106
 None
 0.97A 2cd2A-5b83A:
undetectable		 2cd2A-5b83A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 4 GLN A 107
GLU A 110
ILE A 112
PRO A 113
 None
 0.98A 2fcnA-5b83A:
13.8		 2fcnA-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 4 GLN A 183
GLU A 186
ILE A 188
PRO A 189
 None
 0.90A 2fcnA-5b83A:
13.8		 2fcnA-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 GLN A  31
GLU A  34
ILE A  36
PRO A  37
 None
 1.08A 2fcnA-5b83A:
15.7
2fcnB-5b83A:
15.4		 2fcnA-5b83A:
28.63
2fcnB-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 GLN A 107
GLU A 110
ILE A 112
PRO A 113
 None
 0.59A 2fcnA-5b83A:
15.7
2fcnB-5b83A:
15.4		 2fcnA-5b83A:
28.63
2fcnB-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 GLN A 183
GLU A 186
ILE A 188
PRO A 189
 None
 0.29A 2fcnA-5b83A:
15.7
2fcnB-5b83A:
15.4		 2fcnA-5b83A:
28.63
2fcnB-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 GLN A 259
GLU A 262
ILE A 264
PRO A 265
 None
 0.38A 2fcnA-5b83A:
15.7
2fcnB-5b83A:
15.4		 2fcnA-5b83A:
28.63
2fcnB-5b83A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		3 / 3 SER A  96
GLU A  24
ASP A  21
 None
 0.55A 2zulA-5b83A:
undetectable		 2zulA-5b83A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 11 THR A  85
ILE A  89
LEU A 147
ILE A 112
LEU A 119
 None
 1.19A 3a50C-5b83A:
undetectable		 3a50C-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 12 THR A  85
ILE A  89
LEU A 147
ILE A 112
LEU A 119
 None
 1.16A 3a50E-5b83A:
undetectable		 3a50E-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 11 THR A  85
ILE A  89
ILE A 112
VAL A 102
LEU A 119
 None
 1.19A 3a51A-5b83A:
undetectable		 3a51A-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 12 THR A  85
ILE A  89
ILE A 112
VAL A 102
LEU A 119
 None
 1.17A 3a51C-5b83A:
undetectable		 3a51C-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 12 THR A  85
ILE A  89
ILE A 112
VAL A 102
LEU A 119
 None
 1.18A 3a51D-5b83A:
undetectable		 3a51D-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		5 / 12 THR A  85
ILE A  89
ILE A 112
VAL A 102
LEU A 119
 None
 1.16A 3a51E-5b83A:
undetectable		 3a51E-5b83A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		3 / 3 SER A  96
GLU A  24
ASP A  21
 None
 0.52A 3dmhA-5b83A:
undetectable		 3dmhA-5b83A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 5 VAL A 146
ILE A 120
LEU A 119
ARG A 118
 None
 0.78A 4mghA-5b83A:
undetectable		 4mghA-5b83A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 5 ILE A 106
ARG A 148
ASP A 128
VAL A  93
 None
 1.25A 4nkxC-5b83A:
undetectable		 4nkxC-5b83A:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.77A 4w5oA-5b83A:
undetectable		 4w5oA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.76A 4w5oA-5b83A:
undetectable		 4w5oA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.69A 4w5oA-5b83A:
undetectable		 4w5oA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.74A 4w5qA-5b83A:
undetectable		 4w5qA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.66A 4w5qA-5b83A:
undetectable		 4w5qA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.62A 4w5qA-5b83A:
undetectable		 4w5qA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.95A 4w5tA-5b83A:
undetectable		 4w5tA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.62A 4w5tA-5b83A:
undetectable		 4w5tA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.71A 4w5tA-5b83A:
undetectable		 4w5tA-5b83A:
17.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 4 LEU A   8
ILE A  44
HIS A  68
VAL A  70
 None
 0.86A 4xyzA-5b83A:
14.0		 4xyzA-5b83A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 4 LEU A  84
ILE A 120
HIS A 144
VAL A 146
 None
 1.11A 4xyzA-5b83A:
14.0		 4xyzA-5b83A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 4 LEU A 160
ILE A 196
HIS A 220
VAL A 222
 None
 0.94A 4xyzA-5b83A:
14.0		 4xyzA-5b83A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.79A 4z4cA-5b83A:
undetectable		 4z4cA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.62A 4z4cA-5b83A:
undetectable		 4z4cA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.71A 4z4cA-5b83A:
undetectable		 4z4cA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.76A 4z4dA-5b83A:
undetectable		 4z4dA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.72A 4z4dA-5b83A:
undetectable		 4z4dA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.69A 4z4dA-5b83A:
undetectable		 4z4dA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.78A 4z4eA-5b83A:
undetectable		 4z4eA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.67A 4z4eA-5b83A:
undetectable		 4z4eA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.66A 4z4eA-5b83A:
undetectable		 4z4eA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.76A 4z4gA-5b83A:
undetectable		 4z4gA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.71A 4z4gA-5b83A:
undetectable		 4z4gA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 7 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.68A 4z4gA-5b83A:
undetectable		 4z4gA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 120
GLN A 125
ILE A  99
ASP A 128
 None
 0.87A 6cbdA-5b83A:
undetectable		 6cbdA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 196
GLN A 201
ILE A 175
ASP A 204
 None
 0.66A 6cbdA-5b83A:
undetectable		 6cbdA-5b83A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5b83 TETRA UBIQUITIN
(Homo
sapiens) 		4 / 6 ILE A 272
GLN A 277
ILE A 251
ASP A 280
 None
 0.65A 6cbdA-5b83A:
undetectable		 6cbdA-5b83A:
17.17