SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 9 ASP A  36
ILE A  33
ALA A  31
ILE A 165
THR A  82
 None
 1.38A 1aj6A-5bk6A:
undetectable		 1aj6A-5bk6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		4 / 6 CYH A 175
ASP A  36
VAL A 176
HIS A 142
 None
 1.23A 1ekjG-5bk6A:
2.3
1ekjH-5bk6A:
2.1		 1ekjG-5bk6A:
undetectable
1ekjH-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		4 / 6 HIS A 142
ILE A 140
ALA A  31
VAL A 156
 None
 0.87A 1hk1A-5bk6A:
undetectable		 1hk1A-5bk6A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 HIS A 205
THR A 172
VAL A 176
LYS A 213
ASP A  15
 None
 1.49A 1xihA-5bk6A:
undetectable		 1xihA-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		3 / 3 ARG A 116
ARG A  98
ASP A  89
 None
 0.94A 3wipG-5bk6A:
undetectable
3wipH-5bk6A:
undetectable		 3wipG-5bk6A:
undetectable
3wipH-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 ILE A  65
GLY A 198
CYH A  42
MET A  37
ASP A  54
 None
 0.95A 4iv0B-5bk6A:
undetectable		 4iv0B-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 TYR A  21
ASN A  22
ALA A  24
GLY A  23
LEU A  25
 None
 1.36A 4oadA-5bk6A:
undetectable		 4oadA-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 9 ALA A 208
ILE A  35
GLY A 198
ALA A 199
THR A 200
 None
 1.18A 4r1zA-5bk6A:
undetectable		 4r1zA-5bk6A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 HIS A 205
THR A 172
VAL A 176
LYS A 213
ASP A  15
 None
 1.45A 4xiaA-5bk6A:
undetectable		 4xiaA-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		4 / 5 THR A 168
THR A  30
HIS A  10
LEU A 232
 None
 1.28A 5axaA-5bk6A:
2.7		 5axaA-5bk6A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 10 ILE A  33
ILE A  34
LEU A  69
ILE A 162
ASN A  29
 None
 1.34A 5vkqA-5bk6A:
undetectable
5vkqD-5bk6A:
undetectable		 5vkqA-5bk6A:
undetectable
5vkqD-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 10 ILE A 162
ASN A  29
ILE A  33
ILE A  34
LEU A  69
 None
 1.30A 5vkqA-5bk6A:
undetectable
5vkqB-5bk6A:
undetectable		 5vkqA-5bk6A:
undetectable
5vkqB-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 10 ILE A 162
ASN A  29
ILE A  33
ILE A  34
LEU A  69
 None
 1.31A 5vkqC-5bk6A:
undetectable
5vkqD-5bk6A:
undetectable		 5vkqC-5bk6A:
undetectable
5vkqD-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		4 / 4 TYR A  77
GLY A  23
ASN A  22
ARG A  26
 None
 1.46A 5w7bA-5bk6A:
0.0
5w7bC-5bk6A:
2.1		 5w7bA-5bk6A:
22.50
5w7bC-5bk6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		3 / 3 ARG A 120
ARG A  83
ASP A 141
 None
 0.63A 6d8pA-5bk6A:
undetectable		 6d8pA-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 ILE A  35
GLY A 169
ILE A  65
ILE A 165
ILE A  33
 None
 1.02A 6emuB-5bk6A:
undetectable		 6emuB-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 LEU A 167
GLY A 169
ILE A  65
ILE A 165
ILE A  33
 None
 1.06A 6emuB-5bk6A:
undetectable		 6emuB-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 ILE A  35
GLY A 169
ILE A  65
ILE A 165
ILE A  33
 None
 1.03A 6emuC-5bk6A:
undetectable		 6emuC-5bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5bk6 PUTATIVE AMIDASE
(Rhizobium
leguminosarum) 		5 / 12 LEU A 167
GLY A 169
ILE A  65
ILE A 165
ILE A  33
 None
 1.04A 6emuC-5bk6A:
undetectable		 6emuC-5bk6A:
undetectable