SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		5 / 11 PHE A 229
PHE A 207
LEU A 197
VAL A 274
VAL A 188
 None
 1.25A 1q23J-5bmqA:
undetectable		 1q23J-5bmqA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 6 ASP A 133
PHE A 131
THR A 129
GLU A 139
 None
 1.17A 2dttB-5bmqA:
undetectable
2dttC-5bmqA:
undetectable		 2dttB-5bmqA:
17.84
2dttC-5bmqA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 8 ASN A 275
GLY A 215
THR A 221
GLY A 253
 None
 0.78A 4fo4B-5bmqA:
undetectable		 4fo4B-5bmqA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		5 / 12 ILE A 130
GLY A 128
PHE A 147
GLN A 148
ALA A 132
 None
 1.29A 5n0xB-5bmqA:
undetectable		 5n0xB-5bmqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 5 VAL A 212
THR A 214
VAL A 200
LEU A 288
 None
 1.00A 6bqgA-5bmqA:
undetectable		 6bqgA-5bmqA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 6 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.78A 6e43A-5bmqA:
undetectable		 6e43A-5bmqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 6 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.78A 6e43B-5bmqA:
undetectable		 6e43B-5bmqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 6 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.77A 6e43C-5bmqA:
undetectable		 6e43C-5bmqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN
(Stackebrandtia
nassauensis) 		4 / 6 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.87A 6e43D-5bmqA:
undetectable		 6e43D-5bmqA:
20.34