SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		6 / 12 HIS A 209
TYR A 211
TYR A 295
ASP A 336
ASP A 448
ARG A 496
 None
 1.32A 1dedA-5bn7A:
6.3		 1dedA-5bn7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		6 / 12 HIS A 209
TYR A 295
LEU A 298
ASP A 336
ASP A 448
ARG A 496
 None
 1.27A 1dedA-5bn7A:
6.3		 1dedA-5bn7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 7 PHE A 133
VAL A 194
GLY A 193
ILE A 182
 None
 0.62A 1p2yA-5bn7A:
undetectable		 1p2yA-5bn7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		5 / 12 ILE A 319
ILE A 312
LEU A 335
ILE A 370
HIS A 353
 None
 1.07A 1xzxX-5bn7A:
undetectable		 1xzxX-5bn7A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		3 / 3 ARG A 217
VAL A 248
THR A 213
 None
 0.44A 3cyxA-5bn7A:
undetectable		 3cyxA-5bn7A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		5 / 12 ILE A 319
ILE A 312
LEU A 335
ILE A 370
HIS A 353
 None
 1.03A 3gwsX-5bn7A:
undetectable		 3gwsX-5bn7A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		3 / 3 TRP A 469
TRP A 473
THR A 472
 None
 1.20A 4bboB-5bn7A:
undetectable		 4bboB-5bn7A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 6 SER A 307
GLU A 343
ASP A 291
ASP A 279
 None
 1.20A 4blvA-5bn7A:
undetectable		 4blvA-5bn7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		3 / 3 LYS A 131
TYR A 175
ARG A 132
 None
 1.03A 4gc9A-5bn7A:
undetectable		 4gc9A-5bn7A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 8 ALA A 405
THR A 472
VAL A 555
PHE A 544
 None
 0.92A 4ltwA-5bn7A:
undetectable		 4ltwA-5bn7A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 6 ARG A 135
ASP A 178
VAL A 208
ASP A 131
 None
 1.26A 4xqeA-5bn7A:
undetectable		 4xqeA-5bn7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 6 ARG A 135
ASP A 178
VAL A 208
ASP A 131
 None
 1.22A 4xqeB-5bn7A:
undetectable		 4xqeB-5bn7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		5 / 10 ASP A 180
GLY A 224
PHE A 223
SER A 136
GLY A 177
 None
 1.15A 5i6xA-5bn7A:
undetectable		 5i6xA-5bn7A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		3 / 3 ARG A 132
HIS A 209
ARG A 496
 None
 1.07A 5iaoC-5bn7A:
undetectable		 5iaoC-5bn7A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		3 / 3 ARG A 132
HIS A 209
ARG A 496
 None
 1.08A 5iaoF-5bn7A:
undetectable		 5iaoF-5bn7A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		5 / 10 ILE A 409
LEU A 455
LEU A 463
ALA A 466
LEU A 470
 None
 1.12A 5y7pG-5bn7A:
undetectable		 5y7pG-5bn7A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5bn7 MALTODEXTRIN
GLUCOSIDASE
(Escherichia
coli) 		4 / 6 ARG A 379
ALA A 355
THR A 358
ALA A 384
 None
 1.15A 6ma6A-5bn7A:
undetectable		 6ma6A-5bn7A:
7.87