SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ALA A 106
VAL A 108
TRP A 157
 None
EPE  A 304 ( 4.7A)
None
 0.74A 1bdwA-5bncA:
undetectable
1bdwB-5bncA:
undetectable		 1bdwA-5bncA:
5.58
1bdwB-5bncA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  64
THR A 167
TYR A 172
TYR A  62
 None
 1.48A 1qvuA-5bncA:
undetectable		 1qvuA-5bncA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 6 SER A  40
ILE A  37
ALA A 106
ALA A  98
 None
 0.91A 1w0gA-5bncA:
undetectable		 1w0gA-5bncA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A  57
SER A  58
THR A  48
ASN A  82
 None
EPE  A 302 ( 4.8A)
None
None
 1.13A 1yvpB-5bncA:
undetectable		 1yvpB-5bncA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A  53
HIS A  79
ASP A  75
ASP A  86
 None
EPE  A 302 (-4.4A)
None
None
 0.95A 2oxtB-5bncA:
undetectable		 2oxtB-5bncA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 258
HIS A 195
LEU A 252
ILE A 246
HIS A 190
 None
NI  A 301 (-3.3A)
None
None
NI  A 301 (-3.2A)
 1.32A 3gwxB-5bncA:
undetectable		 3gwxB-5bncA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 191
CYH A 217
LEU A 259
GLY A 241
LEU A 199
 None
 1.35A 3okxA-5bncA:
undetectable		 3okxA-5bncA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 191
CYH A 217
LEU A 259
GLY A 241
LEU A 199
 None
 1.30A 3okxB-5bncA:
1.5		 3okxB-5bncA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 244
ALA A 255
THR A 256
LEU A 259
LEU A 199
 None
 1.02A 3r9cA-5bncA:
undetectable		 3r9cA-5bncA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ARG A 126
LEU A 122
VAL A 147
ASP A 141
 None
 1.04A 3ufnA-5bncA:
undetectable
3ufnB-5bncA:
0.5		 3ufnA-5bncA:
18.07
3ufnB-5bncA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tA-5bncA:
undetectable		 3w9tA-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tB-5bncA:
undetectable		 3w9tB-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tC-5bncA:
undetectable		 3w9tC-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tD-5bncA:
undetectable		 3w9tD-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tE-5bncA:
undetectable		 3w9tE-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.13A 3w9tF-5bncA:
undetectable		 3w9tF-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A 235
GLY A 234
TYR A 209
ASP A 211
 None
 1.12A 3w9tG-5bncA:
undetectable		 3w9tG-5bncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ILE A  91
ILE A  37
SER A  40
LEU A  64
 None
 0.70A 4m51A-5bncA:
undetectable		 4m51A-5bncA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		5 / 9 PRO A  69
LEU A  71
VAL A 133
TYR A  62
LEU A  46
 None
 1.46A 4puoA-5bncA:
undetectable		 4puoA-5bncA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 181
THR A  36
ASP A 178
TYR A 223
 None
 1.41A 4qwpB-5bncA:
undetectable		 4qwpB-5bncA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 5bnc HEME BINDING PROTEIN
MSMEG_6519
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ALA A 114
TRP A 148
VAL A 149
 None
 0.31A 4w9nC-5bncA:
undetectable		 4w9nC-5bncA:
23.19