SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 10 PHE A 385
LEU A 338
ALA A 337
PHE A 491
ILE A 501
 None
 1.05A 1g5yC-5bndA:
undetectable		 1g5yC-5bndA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 11 LEU A 458
LEU A 420
ILE A 448
PRO A 464
LEU A 357
 None
 1.32A 2ft9A-5bndA:
undetectable		 2ft9A-5bndA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 11 LEU A 458
LEU A 420
PRO A 447
ASN A 408
LEU A 357
 None
 1.35A 2ft9A-5bndA:
undetectable		 2ft9A-5bndA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 10 ILE A 360
LEU A 357
VAL A 342
VAL A 384
VAL A 352
 None
 1.04A 2nnjA-5bndA:
undetectable		 2nnjA-5bndA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 11 PHE A 398
ILE A 463
PRO A 464
TRP A 500
TYR A 409
 None
 1.34A 2vcdA-5bndA:
undetectable		 2vcdA-5bndA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		3 / 3 ASN A 417
HIS A 419
VAL A 427
 None
 0.87A 3elzB-5bndA:
undetectable		 3elzB-5bndA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 7 GLU A 498
TRP A 500
LEU A 401
TRP A 482
 None
 1.32A 3k8mA-5bndA:
undetectable		 3k8mA-5bndA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 7 GLU A 498
TRP A 500
LEU A 401
TRP A 482
 None
 1.43A 3k8mB-5bndA:
undetectable		 3k8mB-5bndA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 9 ILE A 448
LEU A 458
PHE A 452
LEU A 338
GLY A 453
 None
 1.40A 3nxuB-5bndA:
undetectable		 3nxuB-5bndA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 8 HIS A 396
LEU A 471
MET A 465
TRP A 500
 None
 1.08A 3uzzB-5bndA:
undetectable		 3uzzB-5bndA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 12 TYR A 386
ASN A 388
ALA A 390
GLY A 391
LEU A 392
 None
 1.47A 4oadA-5bndA:
undetectable		 4oadA-5bndA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 4 GLY A 460
VAL A 462
PHE A 385
ILE A 492
 None
 1.12A 4xv2B-5bndA:
undetectable		 4xv2B-5bndA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 7 TYR A 439
ILE A 451
GLY A 335
LEU A 344
 None
 0.97A 5esmA-5bndA:
undetectable		 5esmA-5bndA:
15.67