SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ISM_A_NCAA303_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 9 LEU A 150
ASP A 160
TRP A 193
SER A 197
GLU A 230
 None
 0.54A 1ismA-5bniA:
26.5		 1ismA-5bniA:
31.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 6 VAL A 246
ILE A 247
TRP A 130
LEU A 147
 None
 1.21A 1j96A-5bniA:
undetectable		 1j96A-5bniA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		3 / 3 TRP A 164
PHE A 192
TRP A 193
 None
 0.44A 1r15C-5bniA:
25.0		 1r15C-5bniA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		3 / 3 TRP A 164
PHE A 192
TRP A 193
 None
 0.42A 1r15F-5bniA:
25.1		 1r15F-5bniA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		3 / 3 TRP A 164
PHE A 192
TRP A 193
 None
 0.43A 1r15G-5bniA:
25.1		 1r15G-5bniA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		3 / 3 TRP A 164
PHE A 192
TRP A 193
 None
 0.44A 1r15H-5bniA:
24.9		 1r15H-5bniA:
28.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 7 LEU A 150
GLU A 151
ASP A 160
TRP A 193
SER A 197
 None
 0.55A 3dzgA-5bniA:
29.3		 3dzgA-5bniA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		6 / 7 LEU A 150
GLU A 151
ASP A 160
TRP A 193
SER A 197
THR A 225
 None
 0.83A 3dzgB-5bniA:
29.5		 3dzgB-5bniA:
55.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 6 LEU A 150
GLU A 151
TRP A 193
SER A 197
 None
 0.33A 3i9jB-5bniA:
24.9		 3i9jB-5bniA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.34A 3jx1A-5bniA:
0.8
3jx1B-5bniA:
undetectable		 3jx1A-5bniA:
20.95
3jx1B-5bniA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 7 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.32A 3n61A-5bniA:
undetectable
3n61B-5bniA:
undetectable		 3n61A-5bniA:
21.19
3n61B-5bniA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.34A 3nlyA-5bniA:
undetectable
3nlyB-5bniA:
undetectable		 3nlyA-5bniA:
20.95
3nlyB-5bniA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 6 LEU A 150
GLU A 151
TRP A 193
SER A 197
THR A 225
 None
 0.70A 3ropA-5bniA:
30.0		 3ropA-5bniA:
55.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.34A 3rqlA-5bniA:
undetectable
3rqlB-5bniA:
undetectable		 3rqlA-5bniA:
20.95
3rqlB-5bniA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.36A 4capA-5bniA:
undetectable
4capB-5bniA:
undetectable		 4capA-5bniA:
20.95
4capB-5bniA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 PHE A  94
SER A 163
VAL A 189
TRP A 193
 None
 1.33A 4d32A-5bniA:
undetectable
4d32B-5bniA:
undetectable		 4d32A-5bniA:
20.95
4d32B-5bniA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP9_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 12 ILE A 173
GLN A  64
ALA A  97
ILE A  67
PHE A  94
 None
 1.25A 4rp9A-5bniA:
undetectable		 4rp9A-5bniA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bni UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 8 SER A 163
VAL A 189
TRP A 193
PHE A  94
 None
 1.30A 5uo7A-5bniA:
undetectable
5uo7B-5bniA:
undetectable		 5uo7A-5bniA:
21.19
5uo7B-5bniA:
21.19