SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5boh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
SER A 221
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
None
 0.61A 1ghmA-5bohA:
17.0		 1ghmA-5bohA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 9 LEU A 193
PHE A 195
LEU A 151
ILE A  92
ALA A  90
 None
None
None
None
KCX  A  86 ( 3.4A)
 0.83A 3mdvA-5bohA:
undetectable		 3mdvA-5bohA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 193
PHE A 195
LEU A 151
ILE A  92
ALA A  90
 None
None
None
None
KCX  A  86 ( 3.4A)
 0.84A 3mdvB-5bohA:
undetectable		 3mdvB-5bohA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.51A 3sh8A-5bohA:
18.7		 3sh8A-5bohA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.50A 3sh8B-5bohA:
18.7		 3sh8B-5bohA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		3 / 3 ARG A 216
GLU A 239
PHE A 237
 None
 0.98A 4kszA-5bohA:
undetectable		 4kszA-5bohA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.52A 4n9kA-5bohA:
18.6		 4n9kA-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.49A 4n9kB-5bohA:
18.7		 4n9kB-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 9 PHE A  57
THR A  59
GLY A 275
VAL A 238
VAL A 246
 None
 1.33A 5cp4A-5bohA:
undetectable		 5cp4A-5bohA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.49A 5ghyA-5bohA:
18.8		 5ghyA-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.49A 5ghyB-5bohA:
18.8		 5ghyB-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 11 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.50A 5ghzA-5bohA:
18.6		 5ghzA-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 10 ALA A  82
SER A  83
SER A 130
LYS A 220
GLY A 222
ARG A 263
 None
KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.51A 5ghzB-5bohA:
18.4		 5ghzB-5bohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 9 LEU A 268
SER A 267
VAL A 238
LEU A 217
ARG A 216
 None
 1.29A 5o96E-5bohA:
undetectable
5o96F-5bohA:
undetectable		 5o96E-5bohA:
22.46
5o96F-5bohA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 9 LEU A 193
ILE A 142
LEU A 138
PHE A 184
ILE A  87
 None
None
None
None
KCX  A  86 ( 4.3A)
 0.92A 5vkqC-5bohA:
undetectable
5vkqD-5bohA:
undetectable		 5vkqC-5bohA:
9.58
5vkqD-5bohA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  83
SER A 130
ARG A 263
LYS A 220
GLY A 222
GLY A 224
 KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
None
KCX  A  86 ( 4.5A)
None
None
 0.90A 6b68D-5bohA:
18.3		 6b68D-5bohA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  83
SER A 130
ARG A 263
LYS A 220
GLY A 222
GLY A 224
 KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
None
KCX  A  86 ( 4.5A)
None
None
 0.85A 6b69D-5bohA:
18.2		 6b69D-5bohA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  83
SER A 130
ARG A 263
LYS A 220
GLY A 222
GLY A 224
 KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
None
KCX  A  86 ( 4.5A)
None
None
 0.85A 6b6aB-5bohA:
18.1		 6b6aB-5bohA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5boh BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 SER A  83
SER A 130
LYS A 220
GLY A 222
GLY A 224
 KCX  A  86 ( 2.7A)
KCX  A  86 ( 3.5A)
KCX  A  86 ( 4.5A)
None
None
 0.39A 6b6aD-5bohA:
18.1		 6b6aD-5bohA:
12.15