SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5boi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
5 / 11 ARG A 423
LEU A 439
GLU A 437
ALA A 319
GLY A 325
None
1.36A 1cmaA-5boiA:
undetectable
1cmaB-5boiA:
undetectable
1cmaA-5boiA:
20.08
1cmaB-5boiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 8 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.89A 1v54P-5boiA:
undetectable
1v54W-5boiA:
undetectable
1v54P-5boiA:
20.21
1v54W-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 7 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.88A 1v55C-5boiA:
undetectable
1v55J-5boiA:
undetectable
1v55C-5boiA:
20.21
1v55J-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 8 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.89A 2dyrP-5boiA:
undetectable
2dyrW-5boiA:
undetectable
2dyrP-5boiA:
20.21
2dyrW-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 7 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.88A 2dysP-5boiA:
undetectable
2dysW-5boiA:
undetectable
2dysP-5boiA:
20.21
2dysW-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 7 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.92A 2eijC-5boiA:
undetectable
2eijJ-5boiA:
undetectable
2eijC-5boiA:
20.21
2eijJ-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 8 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.87A 2eikP-5boiA:
undetectable
2eikW-5boiA:
undetectable
2eikP-5boiA:
20.21
2eikW-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 8 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.91A 2eilC-5boiA:
undetectable
2eilJ-5boiA:
undetectable
2eilC-5boiA:
20.21
2eilJ-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 7 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.92A 2eimC-5boiA:
undetectable
2eimJ-5boiA:
undetectable
2eimC-5boiA:
20.21
2eimJ-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
4 / 7 LYS A 438
LEU A 439
GLN A 440
LEU A 414
None
0.88A 2einC-5boiA:
undetectable
2einJ-5boiA:
undetectable
2einC-5boiA:
20.21
2einJ-5boiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
3 / 3 SER A 359
ASP A 362
ASP A 270
None
0.92A 3iv6C-5boiA:
undetectable
3iv6C-5boiA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
3 / 3 ASP A 352
SER A 349
ARG A 285
None
0.72A 3loqA-5boiA:
undetectable
3loqA-5boiA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)
5boi GERMINATION PROTEIN
YPEB

(Bacillus
megaterium)
3 / 3 PHE A 231
VAL A 281
GLU A 283
None
0.79A 4fvqA-5boiA:
undetectable
4fvqA-5boiA:
19.61