SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3001_1
(SERUM ALBUMIN)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		5 / 11 TYR A  76
TRP A 190
LEU A 171
ARG A 148
HIS A 318
 None
 1.42A 1hk3A-5bovA:
undetectable		 1hk3A-5bovA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ARG A 206
THR A 247
VAL A 244
 None
 0.93A 1hxbA-5bovA:
undetectable		 1hxbA-5bovA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ALA A 155
VAL A 153
TRP A 157
 None
 0.90A 1nt5A-5bovA:
undetectable		 1nt5A-5bovA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ALA A 155
VAL A 153
TRP A 157
 None
 0.90A 1nt5B-5bovA:
undetectable		 1nt5B-5bovA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ARG A 206
THR A 247
VAL A 244
 None
 0.77A 2q64A-5bovA:
undetectable		 2q64A-5bovA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ARG A 206
THR A 247
VAL A 244
 None
 0.85A 2qakA-5bovA:
undetectable		 2qakA-5bovA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		4 / 6 ILE A 152
ARG A 148
PRO A 294
SER A 298
 None
 1.27A 2qd3B-5bovA:
3.1		 2qd3B-5bovA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		4 / 7 LYS A  44
ILE A  45
GLY A  56
LEU A 129
 None
 0.87A 3bjwF-5bovA:
undetectable		 3bjwF-5bovA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		4 / 4 ILE A  55
ARG A  63
ILE A  48
THR A 105
 None
 1.07A 3ia4C-5bovA:
undetectable		 3ia4C-5bovA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ASN A 250
ASN A 116
GLU A 258
 None
 0.92A 3kpdC-5bovA:
undetectable		 3kpdC-5bovA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ASN A 250
ASN A 116
GLU A 258
 None
 0.86A 3kpdB-5bovA:
undetectable		 3kpdB-5bovA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		4 / 6 VAL A 316
VAL A 167
PHE A 328
GLU A 323
 None
 1.43A 3n61A-5bovA:
undetectable
3n61B-5bovA:
undetectable		 3n61A-5bovA:
18.97
3n61B-5bovA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 SER A 168
GLU A 285
GLY A 317
GLY A 290
GLY A 286
 None
 0.96A 3tegA-5bovA:
undetectable		 3tegA-5bovA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		5 / 10 ASP A 144
VAL A 167
GLY A 146
ALA A 147
ALA A 150
 None
 1.24A 3ucjA-5bovA:
undetectable		 3ucjA-5bovA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 ASP A 144
TYR A 192
PHE A 196
TYR A 251
HIS A 318
 None
 0.85A 4j03A-5bovA:
27.8		 4j03A-5bovA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 LEU A 100
MET A 122
ASP A 139
 None
 0.82A 4j7xB-5bovA:
undetectable		 4j7xB-5bovA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 SER A 249
GLU A 268
GLY A 260
LEU A 255
GLY A 256
 None
 1.00A 4yvgA-5bovA:
undetectable		 4yvgA-5bovA:
22.26