SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5bow INTERLEUKIN-1 FAMILY
MEMBER 10
(Homo
sapiens) 		4 / 7 ILE A  57
ILE A  11
PHE A 101
LEU A  27
 None
 0.90A 3adxA-5bowA:
undetectable		 3adxA-5bowA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5bow INTERLEUKIN-1 FAMILY
MEMBER 10
(Homo
sapiens) 		3 / 3 PRO A 125
TYR A  14
GLY A  30
 None
None
EDO  A 205 ( 3.8A)
 0.71A 4g2zA-5bowA:
undetectable		 4g2zA-5bowA:
19.42