SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 5 ARG A  64
ASP A 109
SER A 111
ASN A 130
 SAH  A 303 (-3.1A)
SAH  A 303 (-2.7A)
None
SAH  A 303 (-3.0A)
 0.60A 1kiaB-5bp9A:
12.6		 1kiaB-5bp9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 6 ARG A  64
ASP A 109
SER A 111
ASN A 130
 SAH  A 303 (-3.1A)
SAH  A 303 (-2.7A)
None
SAH  A 303 (-3.0A)
 0.58A 1kiaC-5bp9A:
13.1		 1kiaC-5bp9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A  64
ASP A 109
ASN A 130
 SAH  A 303 (-3.1A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.36A 1nbhA-5bp9A:
13.0		 1nbhA-5bp9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A  64
ASP A 109
ASN A 130
 SAH  A 303 (-3.1A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.33A 1nbhD-5bp9A:
14.1		 1nbhD-5bp9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 HIS A  94
ASP A 109
ASN A 130
 SAH  A 303 (-4.3A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.61A 1wg8B-5bp9A:
10.9		 1wg8B-5bp9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 5 ILE A 108
ILE A  33
ILE A 110
LEU A  96
 None
None
SAH  A 303 ( 4.0A)
None
 0.95A 1zgyA-5bp9A:
undetectable		 1zgyA-5bp9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 6 ARG A  64
ASP A  86
SER A  91
GLY A  92
 SAH  A 303 (-3.1A)
None
None
None
 0.94A 2j2pA-5bp9A:
undetectable
2j2pC-5bp9A:
undetectable		 2j2pA-5bp9A:
21.45
2j2pC-5bp9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 6 ARG A  64
ASP A  86
SER A  91
GLY A  92
 SAH  A 303 (-3.1A)
None
None
None
 0.95A 2j2pD-5bp9A:
undetectable
2j2pF-5bp9A:
undetectable		 2j2pD-5bp9A:
21.45
2j2pF-5bp9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A  88
GLY A  90
ILE A 110
ASN A 130
LEU A 146
 SAH  A 303 (-3.3A)
SAH  A 303 ( 3.7A)
SAH  A 303 ( 4.0A)
SAH  A 303 (-3.0A)
None
 0.72A 3ckkA-5bp9A:
9.3		 3ckkA-5bp9A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A 207
SER A  50
ARG A 209
 None
 1.01A 3loqA-5bp9A:
undetectable		 3loqA-5bp9A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 SER A 114
SER A  91
HIS A  38
 SAH  A 303 ( 4.6A)
None
None
 0.78A 3mzeA-5bp9A:
undetectable		 3mzeA-5bp9A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 11 PHE A 132
GLY A 151
GLY A 149
MET A 178
ILE A 225
 None
 1.39A 3owxA-5bp9A:
undetectable
3owxB-5bp9A:
undetectable		 3owxA-5bp9A:
20.00
3owxB-5bp9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 12 ILE A 152
LEU A 131
LEU A 170
PHE A 163
MET A 166
 SAH  A 303 (-3.7A)
SAH  A 303 (-4.7A)
None
None
None
 1.21A 3vn2A-5bp9A:
undetectable		 3vn2A-5bp9A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A  86
GLY A  88
GLY A  90
ASP A 109
ASN A 130
 None
SAH  A 303 (-3.3A)
SAH  A 303 ( 3.7A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.56A 4dcmA-5bp9A:
10.8		 4dcmA-5bp9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A  88
GLY A  90
ILE A 110
LEU A 131
LEU A 146
 SAH  A 303 (-3.3A)
SAH  A 303 ( 3.7A)
SAH  A 303 ( 4.0A)
SAH  A 303 (-4.7A)
None
 1.01A 4qdjA-5bp9A:
13.8		 4qdjA-5bp9A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A  88
GLY A  90
ILE A 110
SER A 111
LEU A 146
 SAH  A 303 (-3.3A)
SAH  A 303 ( 3.7A)
SAH  A 303 ( 4.0A)
None
None
 0.63A 4qdjA-5bp9A:
13.8		 4qdjA-5bp9A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		4 / 4 CYH A  93
PHE A  63
ILE A  57
GLY A  90
 SAH  A 303 ( 4.2A)
None
None
SAH  A 303 ( 3.7A)
 1.44A 5hesB-5bp9A:
undetectable		 5hesB-5bp9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN
(Bacteroides
fragilis) 		3 / 3 GLY A  90
ASP A 109
ASN A 130
 SAH  A 303 ( 3.7A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.27A 5jglA-5bp9A:
12.0		 5jglA-5bp9A:
21.77