SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bpt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 1.00A 1eqhA-5bptA:
undetectable		 1eqhA-5bptA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 1.01A 1eqhB-5bptA:
undetectable		 1eqhB-5bptA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 6 PHE A 121
GLU A 240
LEU A 238
VAL A 111
 None
 0.86A 1hk1A-5bptA:
2.6		 1hk1A-5bptA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 8 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.42A 1os6A-5bptA:
undetectable		 1os6A-5bptA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 10 LEU A 255
LEU A 135
GLY A 348
ALA A 349
LEU A 353
 None
 1.11A 1pxxA-5bptA:
undetectable		 1pxxA-5bptA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 PRO A 533
ILE A 178
VAL A 170
ILE A 188
LEU A 203
 None
 1.09A 1z9hD-5bptA:
undetectable		 1z9hD-5bptA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 GLY A 704
GLN A 703
VAL A 659
SER A 629
 None
 1.49A 1zzqB-5bptA:
undetectable		 1zzqB-5bptA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 GLY A 704
GLN A 703
VAL A 659
SER A 629
 None
 1.46A 1zzuA-5bptA:
undetectable		 1zzuA-5bptA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 ARG A 732
ILE A  45
PHE A 737
ALA A 724
THR A 644
 None
 1.12A 2j0dA-5bptA:
undetectable		 2j0dA-5bptA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 6 ILE A 693
ARG A 696
ILE A 593
PHE A 581
 None
 1.14A 2q72A-5bptA:
undetectable		 2q72A-5bptA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 TRP A 108
VAL A  31
ARG A 732
 None
 0.87A 3b0wA-5bptA:
undetectable		 3b0wA-5bptA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 ARG A 200
GLU A 215
TYR A 550
 None
 0.90A 3k37B-5bptA:
10.2		 3k37B-5bptA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 8 ASN A 605
LEU A 609
SER A 666
ARG A 696
 None
 1.16A 3kp2A-5bptA:
1.6
3kp2B-5bptA:
1.2		 3kp2A-5bptA:
13.70
3kp2B-5bptA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 1.05A 3n8wA-5bptA:
undetectable		 3n8wA-5bptA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 1.00A 3n8zA-5bptA:
1.9		 3n8zA-5bptA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 PHE A  97
ILE A 188
ALA A 534
THR A 190
LEU A 171
 None
 1.27A 3s79A-5bptA:
undetectable		 3s79A-5bptA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 ASP A  69
ARG A  67
TRP A 108
ILE A  72
 None
 1.27A 3sanA-5bptA:
8.6		 3sanA-5bptA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 ASP A  69
ARG A  67
TRP A 108
ILE A  72
 None
 1.27A 3sanB-5bptA:
7.4		 3sanB-5bptA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 8 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.37A 3selX-5bptA:
undetectable		 3selX-5bptA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 7 ILE A 103
PHE A  97
MET A 185
GLY A 184
 None
 1.24A 3sj0X-5bptA:
undetectable		 3sj0X-5bptA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		6 / 9 ILE A 103
LEU A  99
ILE A  84
PHE A  97
MET A 185
GLY A 184
 None
 1.25A 3sj4X-5bptA:
undetectable		 3sj4X-5bptA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 9 LEU A 530
ILE A  72
LEU A  94
ILE A 148
ILE A 157
 None
 1.28A 3zosB-5bptA:
2.1		 3zosB-5bptA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 GLN A 521
SER A 388
ASP A 381
ILE A 525
ALA A 524
 None
 1.20A 4dx5B-5bptA:
2.9		 4dx5B-5bptA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 TYR A 183
PHE A 121
ARG A 246
 None
 0.95A 4g19D-5bptA:
undetectable		 4g19D-5bptA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 7 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.37A 4hc3A-5bptA:
undetectable		 4hc3A-5bptA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 8 ILE A 103
ILE A  84
PHE A  97
MET A 185
GLY A 184
 None
 1.27A 4hdlA-5bptA:
undetectable		 4hdlA-5bptA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 LEU A 199
ARG A 200
ILE A  17
ASN A 730
 None
 1.49A 4i00A-5bptA:
undetectable		 4i00A-5bptA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 5 ASP A  69
ARG A  67
TRP A 108
ILE A  72
 None
 1.28A 4mwrA-5bptA:
7.7		 4mwrA-5bptA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 ARG A  67
TRP A 108
ILE A  72
 None
 0.81A 4mwxA-5bptA:
7.1		 4mwxA-5bptA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 10 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 0.97A 4ph9A-5bptA:
undetectable		 4ph9A-5bptA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 10 VAL A 241
LEU A 207
GLY A 184
ALA A 182
LEU A 166
 None
 0.99A 4ph9B-5bptA:
undetectable		 4ph9B-5bptA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 ILE A 613
ASP A 657
ARG A 582
 None
 0.80A 4pstA-5bptA:
undetectable		 4pstA-5bptA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 GLY A 176
ILE A 191
SER A 192
LEU A 199
VAL A 212
 None
 1.01A 4qdjA-5bptA:
undetectable		 4qdjA-5bptA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 8 LEU A 547
THR A 225
VAL A 212
SER A 211
 None
 1.09A 4qknA-5bptA:
2.4		 4qknA-5bptA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		5 / 12 PHE A  97
ILE A 188
ALA A 534
THR A 190
LEU A 171
 None
 1.26A 5jkvA-5bptA:
undetectable		 5jkvA-5bptA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 LYS A 247
HIS A 355
HIS A 250
 None
 0.77A 5oexA-5bptA:
7.1		 5oexA-5bptA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 LYS A 247
HIS A 355
HIS A 250
 None
 0.85A 5oexB-5bptA:
5.7		 5oexB-5bptA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 LYS A 247
HIS A 355
HIS A 250
 None
 0.81A 5oexC-5bptA:
8.5		 5oexC-5bptA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		3 / 3 LYS A 247
HIS A 355
HIS A 250
 None
 0.78A 5oexD-5bptA:
6.7		 5oexD-5bptA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5bpt MGC81278 PROTEIN
(Xenopus
laevis) 		4 / 8 GLY A 361
LEU A 364
ALA A 376
LYS A 377
 None
 0.83A 6mdqA-5bptA:
undetectable		 6mdqA-5bptA:
8.85