SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		5 / 12 GLY A 295
GLY A  67
GLY A  68
ALA A  72
PRO A  54
 None
 0.86A 2dpmA-5bq3A:
undetectable		 2dpmA-5bq3A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		4 / 5 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.22A 3bjwA-5bq3A:
undetectable		 3bjwA-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		4 / 5 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.18A 3bjwG-5bq3A:
undetectable		 3bjwG-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		4 / 5 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.21A 3bjwC-5bq3A:
undetectable		 3bjwC-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		4 / 5 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.25A 3bjwD-5bq3A:
undetectable		 3bjwD-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		4 / 7 PHE A  61
PHE A 352
THR A 244
PHE A 342
 None
 0.98A 3vnsA-5bq3A:
3.7		 3vnsA-5bq3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		5 / 12 PHE A 352
ALA A 292
PHE A  61
PHE A 286
GLY A 337
 None
 1.21A 4kykA-5bq3A:
undetectable
4kykB-5bq3A:
undetectable		 4kykA-5bq3A:
18.84
4kykB-5bq3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 ASN A 331
ASP A 139
ASP A 117
 None
 0.60A 4obwD-5bq3A:
undetectable		 4obwD-5bq3A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 GLN A 187
THR A 243
ASP A 217
 None
 0.93A 5k9dA-5bq3A:
undetectable		 5k9dA-5bq3A:
22.96