SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5bq5 INSERTION SEQUENCE
IS5376 PUTATIVE
ATP-BINDING PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 169
SER A 198
MET A 168
LEU A 196
LEU A 104
 None
 1.07A 1a8uA-5bq5A:
undetectable		 1a8uA-5bq5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5bq5 INSERTION SEQUENCE
IS5376 PUTATIVE
ATP-BINDING PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 169
SER A 198
MET A 168
LEU A 196
LEU A 104
 None
 1.04A 1a8uB-5bq5A:
undetectable		 1a8uB-5bq5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5bq5 INSERTION SEQUENCE
IS5376 PUTATIVE
ATP-BINDING PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 LEU A 114
PHE A 103
THR A  91
LEU A  90
 None
 0.91A 3ag3N-5bq5A:
undetectable
3ag3W-5bq5A:
undetectable		 3ag3N-5bq5A:
18.66
3ag3W-5bq5A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5bq5 INSERTION SEQUENCE
IS5376 PUTATIVE
ATP-BINDING PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 112
LYS A 153
GLU A 167
 MG  A 302 ( 3.1A)
None
BEF  A 303 ( 4.9A)
 1.02A 3ijdB-5bq5A:
undetectable		 3ijdB-5bq5A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 5bq5 INSERTION SEQUENCE
IS5376 PUTATIVE
ATP-BINDING PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 5 ASP A  74
PHE A  75
PHE A  73
VAL A  81
 None
None
ADP  A 301 (-2.9A)
None
 0.97A 5a1rA-5bq5A:
undetectable		 5a1rA-5bq5A:
18.35