SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_A_IPHA802_0 (PHENOL HYDROXYLASE)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 10	ASP A 106 GLY A 104 ARG A 98 TYR A 32 GLY A 101	None	1.28A	1fohA-5bq7A: undetectable	1fohA-5bq7A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_B_IPHB802_0 (PHENOL HYDROXYLASE)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 10	ASP A 106 GLY A 104 ARG A 98 TYR A 32 GLY A 101	None	1.28A	1fohB-5bq7A: undetectable	1fohB-5bq7A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_C_IPHC802_0 (PHENOL HYDROXYLASE)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 10	ASP A 106 GLY A 104 ARG A 98 TYR A 32 GLY A 101	None	1.28A	1fohC-5bq7A: undetectable	1fohC-5bq7A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_D_IPHD802_0 (PHENOL HYDROXYLASE)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 10	ASP A 106 GLY A 104 ARG A 98 TYR A 32 GLY A 101	None	1.29A	1fohD-5bq7A: undetectable	1fohD-5bq7A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	4 / 7	ALA A 92 THR A 91 VAL A 114 GLU A 89	None	0.73A	5ecmD-5bq7A: undetectable	5ecmD-5bq7A: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	4 / 7	ALA A 92 THR A 91 VAL A 114 GLU A 89	None	0.77A	5ecoD-5bq7A: undetectable	5ecoD-5bq7A: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 12	ALA A 141 GLY A 167 LYS A 134 SER A 135 PRO A 131	None	1.36A	5zvgA-5bq7A: undetectable	5zvgA-5bq7A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	5bq7	FAB 5F-10-HEAVY CHAIN (Homo sapiens)	5 / 12	ALA A 141 GLY A 167 LYS A 134 SER A 135 PRO A 131	None	1.32A	5zvgB-5bq7A: undetectable	5zvgB-5bq7A: 19.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FOH_A_IPHA802_0","PHENOL HYDROXYLASE","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ASP A 106;GLY A 104;ARG A  98;TYR A  32;GLY A 101","None","1.28A","1fohA-5bq7A:undetectable","1fohA-5bq7A:17.51"],["1FOH_B_IPHB802_0","PHENOL HYDROXYLASE","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ASP A 106;GLY A 104;ARG A  98;TYR A  32;GLY A 101","None","1.28A","1fohB-5bq7A:undetectable","1fohB-5bq7A:17.51"],["1FOH_C_IPHC802_0","PHENOL HYDROXYLASE","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ASP A 106;GLY A 104;ARG A  98;TYR A  32;GLY A 101","None","1.28A","1fohC-5bq7A:undetectable","1fohC-5bq7A:17.51"],["1FOH_D_IPHD802_0","PHENOL HYDROXYLASE","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ASP A 106;GLY A 104;ARG A  98;TYR A  32;GLY A 101","None","1.29A","1fohD-5bq7A:undetectable","1fohD-5bq7A:17.51"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",4,"ALA A  92;THR A  91;VAL A 114;GLU A  89","None","0.73A","5ecmD-5bq7A:undetectable","5ecmD-5bq7A:21.25"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",4,"ALA A  92;THR A  91;VAL A 114;GLU A  89","None","0.77A","5ecoD-5bq7A:undetectable","5ecoD-5bq7A:21.25"],["5ZVG_A_SAMA401_0","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ALA A 141;GLY A 167;LYS A 134;SER A 135;PRO A 131","None","1.36A","5zvgA-5bq7A:undetectable","5zvgA-5bq7A:19.44"],["5ZVG_B_SAMB401_0","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","5bq7","FAB 5F-10-HEAVY CHAIN","Homo sapiens",5,"ALA A 141;GLY A 167;LYS A 134;SER A 135;PRO A 131","None","1.32A","5zvgB-5bq7A:undetectable","5zvgB-5bq7A:19.44"]]