SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 6 HIS A 112
LEU A 123
LEU A 116
PRO A 117
 None
 1.32A 1hz4A-5bq9A:
undetectable		 1hz4A-5bq9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 5 ILE A 547
ARG A 373
ASP A 351
ASN A 347
 None
 1.36A 1kiaD-5bq9A:
undetectable		 1kiaD-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		3 / 3 ARG A 373
ASP A 351
ASN A 347
 None
 0.87A 1nbhA-5bq9A:
undetectable		 1nbhA-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		3 / 3 ARG A 373
ASP A 351
ASN A 347
 None
 0.85A 1nbhD-5bq9A:
undetectable		 1nbhD-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 4 ILE A 547
ARG A 373
ASP A 351
ASN A 347
 None
 1.23A 1nbiC-5bq9A:
undetectable		 1nbiC-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 4 ILE A 547
ARG A 373
ASP A 351
ASN A 347
 None
 1.23A 1nbiD-5bq9A:
undetectable		 1nbiD-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_2
(BILE ACID RECEPTOR)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 4 MET A 409
MET A 500
ALA A 501
HIS A 504
 None
 1.09A 1ot7A-5bq9A:
2.1		 1ot7A-5bq9A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 8 ASP A 552
PHE A 568
LEU A 354
ASP A 351
 None
 1.03A 1rmtD-5bq9A:
undetectable		 1rmtD-5bq9A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 LEU A  16
GLY A  67
ILE A  18
VAL A  47
LEU A  46
 None
 0.89A 1uakA-5bq9A:
undetectable		 1uakA-5bq9A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 6 SER A 466
ILE A 133
ALA A 303
ALA A 308
 None
 0.92A 1w0gA-5bq9A:
1.8		 1w0gA-5bq9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 ILE A 547
VAL A 548
PHE A 517
TYR A 542
LEU A 377
 None
 1.24A 1wsvA-5bq9A:
undetectable		 1wsvA-5bq9A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		3 / 3 TYR A 445
HIS A 366
ARG A 416
 None
 1.04A 4htfA-5bq9A:
undetectable		 4htfA-5bq9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 GLU A  57
ILE A  89
LEU A  85
GLY A  67
ASN A  64
 None
 1.11A 4o1eB-5bq9A:
undetectable		 4o1eB-5bq9A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 ILE A  89
LEU A  85
GLY A  67
ASN A  64
ILE A  56
 None
 0.91A 4o1eB-5bq9A:
undetectable		 4o1eB-5bq9A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		6 / 12 PHE A  44
GLY A  67
ILE A  56
LEU A  85
PHE A  88
LEU A  90
 None
 1.49A 4pd4C-5bq9A:
undetectable		 4pd4C-5bq9A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 TYR A 445
ILE A 414
GLY A 415
PHE A 411
HIS A 366
 None
 1.12A 4rvdA-5bq9A:
undetectable		 4rvdA-5bq9A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		3 / 3 TRP A 481
ILE A 492
SER A 494
 None
 0.99A 5gqbA-5bq9A:
undetectable		 5gqbA-5bq9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 6 VAL A  95
HIS A  99
HIS A 112
LEU A 116
 None
 1.07A 5hrqH-5bq9A:
undetectable
5hrqK-5bq9A:
undetectable
5hrqL-5bq9A:
undetectable		 5hrqH-5bq9A:
4.38
5hrqK-5bq9A:
3.09
5hrqL-5bq9A:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 5 HIS A 366
HIS A 370
HIS A 504
VAL A 413
 None
 1.39A 5i3bB-5bq9A:
undetectable		 5i3bB-5bq9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5bq9 UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 7 HIS A 443
HIS A 366
ASP A 424
GLU A 343
 None
 1.29A 6mn4F-5bq9A:
undetectable		 6mn4F-5bq9A:
19.04