SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		4 / 6 ARG A 201
GLY A 160
THR A 180
ARG A  96
 NRQ  A  67 ( 3.8A)
None
None
NRQ  A  67 ( 2.5A)
 1.03A 2f7fA-5bqlA:
undetectable		 2f7fA-5bqlA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		5 / 12 LEU A 119
MET A  13
LEU A   8
THR A  72
PHE A  92
 None
 1.46A 2oaxA-5bqlA:
undetectable		 2oaxA-5bqlA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		5 / 12 GLN A 138
GLY A 143
VAL A 169
ASP A  60
ALA A  58
 None
 1.14A 3d91B-5bqlA:
undetectable		 3d91B-5bqlA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		4 / 8 ARG A 201
ALA A 223
LEU A  80
ASP A  82
 NRQ  A  67 ( 3.8A)
None
None
None
 0.78A 3qj7A-5bqlA:
undetectable
3qj7D-5bqlA:
undetectable		 3qj7A-5bqlA:
20.58
3qj7D-5bqlA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		5 / 10 LEU A  62
LEU A 203
ILE A  47
LEU A  19
PHE A  59
 None
NRQ  A  67 ( 4.2A)
None
None
None
 1.07A 4odoA-5bqlA:
undetectable		 4odoA-5bqlA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		3 / 3 PRO A 194
MET A 193
TYR A  83
 None
 0.78A 4qa0B-5bqlA:
undetectable		 4qa0B-5bqlA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		3 / 3 PRO A 194
MET A 193
TYR A  83
 None
 0.78A 4qa0A-5bqlA:
undetectable		 4qa0A-5bqlA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		3 / 3 PRO A 194
MET A 193
TYR A  83
 None
 0.82A 4qa2B-5bqlA:
undetectable		 4qa2B-5bqlA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		3 / 3 TYR A 121
TYR A  83
SER A  87
 NRQ  A  67 ( 4.5A)
None
None
 1.00A 5iktB-5bqlA:
undetectable		 5iktB-5bqlA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5bql FLUORESCENT PROTEIN
CYOFP
(Escherichia
coli) 		4 / 5 TYR A  83
TYR A 182
GLY A 157
GLY A 156
 None
 1.20A 5x7pA-5bqlA:
undetectable		 5x7pA-5bqlA:
11.70