SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 5 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.27A 4k4yA-5bqzA:
undetectable		 4k4yA-5bqzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 4 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.29A 4k4yE-5bqzA:
undetectable		 4k4yE-5bqzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 5 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.27A 4k4yI-5bqzA:
undetectable		 4k4yI-5bqzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1322_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 4 GLU A  81
THR A  56
GLU A  58
LYS A 102
 None
 1.42A 4mghA-5bqzA:
0.0		 4mghA-5bqzA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 5 ARG A  40
GLY A 285
GLU A  38
ARG A  82
 None
 1.16A 5cdqA-5bqzA:
undetectable
5cdqB-5bqzA:
undetectable
5cdqC-5bqzA:
undetectable		 5cdqA-5bqzA:
20.42
5cdqB-5bqzA:
18.60
5cdqC-5bqzA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMW_A_PNNA305_0
(BETA-LACTAMASE
TOHO-1)		 5bqz HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 4 ASN A 270
PRO A  83
ASN A  84
ASP A  54
 None
 1.45A 5kmwA-5bqzA:
undetectable		 5kmwA-5bqzA:
23.03