SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		5 / 12 ALA A 286
ALA A 289
LEU A 313
ALA A 284
LEU A 319
 None
 1.05A 1xiuB-5braA:
undetectable		 1xiuB-5braA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		5 / 12 GLN A 180
GLY A 173
ILE A 278
GLY A 233
ALA A 240
 None
 0.97A 3sudC-5braA:
undetectable		 3sudC-5braA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		5 / 12 GLN A 180
GLY A 173
ILE A 278
GLY A 233
ALA A 240
 None
 1.00A 3sufB-5braA:
undetectable		 3sufB-5braA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		4 / 5 ARG A  59
LEU A 262
VAL A 263
ASP A 282
 None
 1.04A 3ufnA-5braA:
undetectable
3ufnB-5braA:
undetectable		 3ufnA-5braA:
16.15
3ufnB-5braA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		3 / 4 SER A 133
GLY A 186
GLU A 200
 None
 0.60A 4juoA-5braA:
undetectable
4juoC-5braA:
3.4		 4juoA-5braA:
23.71
4juoC-5braA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		4 / 8 THR A 171
THR A 170
TYR A 168
TRP A 281
 None
 1.25A 5x2sI-5braA:
undetectable
5x2sJ-5braA:
undetectable
5x2sK-5braA:
undetectable		 5x2sI-5braA:
18.29
5x2sJ-5braA:
18.34
5x2sK-5braA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		5 / 12 PHE A  67
ILE A 128
ILE A  91
LEU A  95
ILE A  45
 None
 1.05A 5y2tB-5braA:
undetectable		 5y2tB-5braA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 5bra PUTATIVE PERIPLASMIC
BINDING PROTEIN WITH
SUBSTRATE RIBOSE
(Ochrobactrum
anthropi) 		5 / 12 GLN A 180
GLY A 173
ILE A 278
GLY A 233
ALA A 240
 None
 1.01A 6c2mB-5braA:
undetectable		 6c2mB-5braA:
13.45