SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5brj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_1 (SUN PROTEIN)	5brj	TWO COMPONENT RESPONSE REGULATOR (Agrobacterium tumefaciens)	3 / 3	PRO A 69 ASP A 72 ASP A 65	None None MG A 201 (-2.5A)	0.77A	1sqfA-5brjA: 3.2	1sqfA-5brjA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9X_A_NIMA1_1 (LACTOTRANSFERRIN')	5brj	TWO COMPONENT RESPONSE REGULATOR (Agrobacterium tumefaciens)	4 / 4	GLU A 75 GLY A 38 THR A 39 GLU A 40	None	0.92A	3e9xA-5brjA: 1.9	3e9xA-5brjA: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	5brj	TWO COMPONENT RESPONSE REGULATOR (Agrobacterium tumefaciens)	3 / 3	TYR A 107 ASP A 72 ASP A 11	None None MG A 201 (-2.5A)	0.85A	3ou6B-5brjA: undetectable	3ou6B-5brjA: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_C_ACTC1740_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT)	5brj	TWO COMPONENT RESPONSE REGULATOR (Agrobacterium tumefaciens)	4 / 4	VAL A 76 GLU A 75 GLY A 38 LEU A 42	None	0.98A	5g5gC-5brjA: undetectable	5g5gC-5brjA: 11.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SQF_A_SAMA430_1","SUN PROTEIN","5brj","TWO COMPONENT RESPONSE REGULATOR","Agrobacterium tumefaciens",3,"PRO A  69;ASP A  72;ASP A  65","None;None; MG A 201 (-2.5A)","0.77A","1sqfA-5brjA:3.2","1sqfA-5brjA:17.06"],["3E9X_A_NIMA1_1","LACTOTRANSFERRIN'","5brj","TWO COMPONENT RESPONSE REGULATOR","Agrobacterium tumefaciens",4,"GLU A  75;GLY A  38;THR A  39;GLU A  40","None","0.92A","3e9xA-5brjA:1.9","3e9xA-5brjA:18.42"],["3OU6_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","5brj","TWO COMPONENT RESPONSE REGULATOR","Agrobacterium tumefaciens",3,"TYR A 107;ASP A  72;ASP A  11","None;None; MG A 201 (-2.5A)","0.85A","3ou6B-5brjA:undetectable","3ou6B-5brjA:24.23"],["5G5G_C_ACTC1740_0","PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT","5brj","TWO COMPONENT RESPONSE REGULATOR","Agrobacterium tumefaciens",4,"VAL A  76;GLU A  75;GLY A  38;LEU A  42","None","0.98A","5g5gC-5brjA:undetectable","5g5gC-5brjA:11.83"]]