SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bt8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  48
ALA A 168
VAL A  54
MET A   6
LEU A  11
 None
 1.33A 1aqbA-5bt8A:
undetectable		 1aqbA-5bt8A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  48
ALA A 168
VAL A  54
MET A   6
LEU A  11
 None
 1.45A 1kt6A-5bt8A:
undetectable		 1kt6A-5bt8A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 5 LEU A  11
VAL A  16
CYH A 133
ALA A 130
 None
 0.85A 1mz9D-5bt8A:
undetectable		 1mz9D-5bt8A:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 108
LEU A  81
VAL A  24
ALA A  40
ALA A  39
 None
 1.11A 1n5xA-5bt8A:
undetectable		 1n5xA-5bt8A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 108
LEU A  81
VAL A  24
ALA A  40
ALA A  39
 None
 1.11A 1n5xB-5bt8A:
undetectable		 1n5xB-5bt8A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 ARG A 113
ILE A  18
ALA A 144
ARG A 146
GLU A 148
 None
 1.10A 2j0dA-5bt8A:
undetectable		 2j0dA-5bt8A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 9 ASP A 352
VAL A 322
GLY A 216
ILE A 217
THR A 332
 None
 1.23A 3el4B-5bt8A:
undetectable		 3el4B-5bt8A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 8 ALA A 305
ILE A 307
ASN A 306
PRO A 252
 None
 0.93A 3fxrA-5bt8A:
undetectable		 3fxrA-5bt8A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 GLU A 170
GLY A 142
VAL A 200
GLY A 349
ARG A  36
 None
 1.09A 3k13A-5bt8A:
undetectable		 3k13A-5bt8A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 7 GLY A 350
GLY A 191
PHE A 379
PHE A 141
 None
 0.91A 3ko0M-5bt8A:
undetectable
3ko0P-5bt8A:
undetectable		 3ko0M-5bt8A:
14.96
3ko0P-5bt8A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 THR A 300
ASP A 295
GLY A 331
ALA A 334
ALA A 338
 None
 0.94A 3p5nA-5bt8A:
undetectable		 3p5nA-5bt8A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 THR A 300
ASP A 295
GLY A 331
ALA A 334
ALA A 338
 None
 0.95A 3p5nB-5bt8A:
undetectable		 3p5nB-5bt8A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 VAL A 189
ALA A 190
GLY A 191
ALA A 356
LEU A 315
 None
 1.12A 3qxyA-5bt8A:
undetectable		 3qxyA-5bt8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 11 VAL A 189
ALA A 190
GLY A 191
ALA A 356
LEU A 315
 None
 1.14A 3rc0A-5bt8A:
undetectable		 3rc0A-5bt8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 VAL A 189
ALA A 190
GLY A 191
ALA A 356
LEU A 315
 None
 1.13A 3rc0B-5bt8A:
undetectable		 3rc0B-5bt8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 7 TYR A 368
LEU A 166
ALA A 168
ASP A 139
 None
 1.18A 3rodD-5bt8A:
undetectable		 3rodD-5bt8A:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		3 / 3 HIS A 145
SER A 150
GLU A 148
 None
 0.73A 3s8pA-5bt8A:
undetectable		 3s8pA-5bt8A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 6 ARG A  36
GLU A  20
LEU A 166
ASP A  21
 None
 1.06A 4cevE-5bt8A:
4.6
4cevF-5bt8A:
4.4		 4cevE-5bt8A:
22.33
4cevF-5bt8A:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		6 / 12 GLY A 191
GLY A 215
GLY A 216
LEU A 233
MET A 292
LEU A 294
 None
 0.91A 4o33A-5bt8A:
44.0		 4o33A-5bt8A:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		6 / 12 GLY A 215
GLY A 216
LEU A 233
MET A 292
LEU A 294
VAL A 322
 None
 0.81A 4o33A-5bt8A:
44.0		 4o33A-5bt8A:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		6 / 12 GLY A 215
LEU A 233
MET A 292
LEU A 294
GLY A 321
VAL A 322
 None
 0.78A 4o33A-5bt8A:
44.0		 4o33A-5bt8A:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 191
GLY A 215
GLY A 216
LEU A 233
MET A 292
 None
 0.88A 4o3fA-5bt8A:
42.9		 4o3fA-5bt8A:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		6 / 12 GLY A 191
GLY A 215
LEU A 233
MET A 292
LEU A 294
VAL A 322
 None
 0.82A 4o3fA-5bt8A:
42.9		 4o3fA-5bt8A:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		6 / 12 GLY A 215
LEU A 233
MET A 292
LEU A 294
GLY A 321
VAL A 322
 None
 0.71A 4o3fA-5bt8A:
42.9		 4o3fA-5bt8A:
41.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		4 / 6 TYR A 368
GLY A 372
GLU A 170
ASP A  21
 None
 1.15A 5emlA-5bt8A:
3.9		 5emlA-5bt8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 VAL A 112
LEU A  60
VAL A  77
LEU A  81
ILE A  44
 None
 1.05A 5mugA-5bt8A:
undetectable		 5mugA-5bt8A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 THR A 332
VAL A 296
VAL A 258
ASP A 352
ASN A 219
 None
 1.50A 6iblB-5bt8A:
undetectable		 6iblB-5bt8A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5bt8 PHOSPHOGLYCERATE
KINASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 214
GLY A 191
VAL A 194
ASP A 295
PHE A 221
 None
 1.03A 6nj9K-5bt8A:
2.9		 6nj9K-5bt8A:
24.18