SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5btb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 11 THR A 316
LEU A  18
VAL A 205
GLY A 204
VAL A 109
 None
 1.19A 1akdA-5btbA:
undetectable		 1akdA-5btbA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 11 THR A 316
LEU A  18
VAL A 205
GLY A 204
VAL A 109
 None
 1.22A 1phgA-5btbA:
undetectable		 1phgA-5btbA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 12 LEU A 264
LEU A 260
ILE A 309
ILE A 102
LEU A 210
 None
 1.12A 1tw4A-5btbA:
undetectable		 1tw4A-5btbA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 12 LEU A 264
LEU A 260
ILE A 309
ILE A 102
LEU A 210
 None
 1.10A 1tw4B-5btbA:
undetectable		 1tw4B-5btbA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 11 THR A 316
LEU A  18
VAL A 205
GLY A 204
VAL A 109
 None
 1.16A 2a1nA-5btbA:
undetectable		 2a1nA-5btbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 8 LEU A 260
LEU A 315
VAL A 205
GLY A 204
 None
 0.96A 2po5A-5btbA:
undetectable		 2po5A-5btbA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 6 ALA A 341
LEU A   9
ALA A 121
THR A 122
 None
 0.89A 3b6hA-5btbA:
undetectable		 3b6hA-5btbA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 6 ALA A 341
LEU A   9
ALA A 121
THR A 122
 None
 0.86A 3b6hB-5btbA:
undetectable		 3b6hB-5btbA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 6 ILE A 219
LEU A  43
MET A  38
GLY A  25
 None
 1.03A 3sj1X-5btbA:
undetectable		 3sj1X-5btbA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5btb AFR263CP
(Eremothecium
gossypii) 		3 / 3 LYS A 282
VAL A 280
HIS A  56
 None
 1.06A 3tj7A-5btbA:
undetectable		 3tj7A-5btbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 7 ILE A 219
LEU A  43
MET A  38
GLY A  25
 None
 1.06A 4hbfA-5btbA:
undetectable		 4hbfA-5btbA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 7 ILE A 219
LEU A  43
MET A  38
GLY A  25
 None
 1.06A 4hc3A-5btbA:
undetectable		 4hc3A-5btbA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 9 THR A 316
LEU A  18
VAL A 205
GLY A 204
VAL A 109
 None
 1.16A 5cp4A-5btbA:
undetectable		 5cp4A-5btbA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 5btb AFR263CP
(Eremothecium
gossypii) 		4 / 4 VAL A 216
GLU A 215
GLY A 218
LEU A  43
 None
 1.34A 5g5gC-5btbA:
0.2		 5g5gC-5btbA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 11 GLU A 286
GLY A 218
ASP A 217
ILE A 267
VAL A 216
 None
 1.08A 5yk2A-5btbA:
undetectable		 5yk2A-5btbA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5btb AFR263CP
(Eremothecium
gossypii) 		3 / 3 ASN A  42
PRO A 195
GLN A  70
 None
 0.93A 6jnhA-5btbA:
2.1		 6jnhA-5btbA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5btb AFR263CP
(Eremothecium
gossypii) 		3 / 3 ASN A  42
PRO A 195
GLN A  70
 None
 0.94A 6jogA-5btbA:
undetectable		 6jogA-5btbA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 5btb AFR263CP
(Eremothecium
gossypii) 		5 / 12 PRO A 293
ILE A 309
LEU A 210
LEU A 260
ILE A 113
 None
 1.05A 6qxsD-5btbA:
undetectable		 6qxsD-5btbA:
20.42