SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		3 / 3 ALA A 174
THR A 241
PHE A 124
 None
 0.72A 2c6nB-5bu6A:
undetectable		 2c6nB-5bu6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 12 SER A  47
THR A  42
ARG A 290
ILE A 288
PHE A  43
 None
None
SCN  A 404 (-4.1A)
None
None
 1.15A 2vdyA-5bu6A:
undetectable		 2vdyA-5bu6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ASP A  95
ILE A  93
LEU A 285
GLU A 180
 None
None
None
EDO  A 408 (-3.7A)
 0.96A 2ya7A-5bu6A:
undetectable		 2ya7A-5bu6A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ASP A  95
ILE A  93
LEU A 285
GLU A 180
 None
None
None
EDO  A 408 (-3.7A)
 0.98A 2ya7D-5bu6A:
undetectable		 2ya7D-5bu6A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 VAL A 139
HIS A 189
ASP A 114
VAL A 159
 None
NI  A 401 ( 3.3A)
NI  A 401 (-2.5A)
None
 0.81A 3fi0B-5bu6A:
undetectable		 3fi0B-5bu6A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 VAL A 139
HIS A 189
ASP A 114
VAL A 159
 None
NI  A 401 ( 3.3A)
NI  A 401 (-2.5A)
None
 0.76A 3fi0G-5bu6A:
undetectable		 3fi0G-5bu6A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 VAL A 139
HIS A 189
ASP A 114
VAL A 159
 None
NI  A 401 ( 3.3A)
NI  A 401 (-2.5A)
None
 0.78A 3fi0Q-5bu6A:
undetectable		 3fi0Q-5bu6A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 MET A  90
VAL A 135
LEU A  76
ILE A 270
 None
 0.93A 3gcsA-5bu6A:
undetectable		 3gcsA-5bu6A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		3 / 3 TYR A 252
ASP A 114
ASP A  50
 None
NI  A 401 (-2.5A)
None
 0.90A 3ou6B-5bu6A:
undetectable		 3ou6B-5bu6A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 VAL A 139
TRP A 142
HIS A 189
PHE A 164
 None
None
NI  A 401 ( 3.3A)
None
 1.19A 3v35A-5bu6A:
4.8		 3v35A-5bu6A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 12 SER A  47
THR A  42
ARG A 290
ILE A 288
PHE A  43
 None
None
SCN  A 404 (-4.1A)
None
None
 1.22A 4c49C-5bu6A:
undetectable		 4c49C-5bu6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 PRO A 281
ARG A  97
GLY A  99
GLN A  91
 None
 0.95A 4g0uA-5bu6A:
undetectable		 4g0uA-5bu6A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 7 THR A 259
GLN A 287
ALA A 263
ILE A 248
 None
 0.96A 4txnD-5bu6A:
undetectable		 4txnD-5bu6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		3 / 3 VAL A 283
THR A 280
ARG A 289
 None
 0.77A 5b2sB-5bu6A:
0.0		 5b2sB-5bu6A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 7 ILE A  93
ARG A 289
THR A 273
LEU A 272
 None
 0.85A 5b3sN-5bu6A:
undetectable
5b3sW-5bu6A:
undetectable		 5b3sN-5bu6A:
18.29
5b3sW-5bu6A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 5 ALA A  57
HIS A 189
MET A  62
LEU A  55
 None
NI  A 401 ( 3.3A)
None
None
 1.39A 5dzkb-5bu6A:
0.6
5dzkp-5bu6A:
undetectable		 5dzkb-5bu6A:
22.22
5dzkp-5bu6A:
2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 5 ALA A  57
HIS A 189
MET A  62
LEU A  55
 None
NI  A 401 ( 3.3A)
None
None
 1.43A 5dzkc-5bu6A:
undetectable
5dzkq-5bu6A:
undetectable		 5dzkc-5bu6A:
22.22
5dzkq-5bu6A:
2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 5 ALA A  57
HIS A 189
MET A  62
LEU A  55
 None
NI  A 401 ( 3.3A)
None
None
 1.47A 5dzkf-5bu6A:
undetectable
5dzkt-5bu6A:
undetectable		 5dzkf-5bu6A:
22.22
5dzkt-5bu6A:
2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ASP A 113
ASP A 114
HIS A 184
HIS A 189
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
 0.49A 5ncdA-5bu6A:
9.3
5ncdD-5bu6A:
3.1		 5ncdA-5bu6A:
21.45
5ncdD-5bu6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ASP A 113
ASP A 114
HIS A 184
HIS A 189
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
 0.55A 5ncdB-5bu6A:
3.0
5ncdC-5bu6A:
9.4		 5ncdB-5bu6A:
21.45
5ncdC-5bu6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 8 ASP A 113
ASP A 114
HIS A 184
HIS A 189
PRO A 251
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
SCN  A 404 ( 4.7A)
 0.48A 5nekB-5bu6A:
9.3		 5nekB-5bu6A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 ASP A 113
ASP A 114
HIS A 184
HIS A 189
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
 0.58A 5nekD-5bu6A:
9.4		 5nekD-5bu6A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 6 ASP A 113
ASP A 114
HIS A 184
HIS A 189
HIS A  49
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
None
 1.33A 5nelA-5bu6A:
3.2
5nelD-5bu6A:
2.4		 5nelA-5bu6A:
21.45
5nelD-5bu6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ILE A  93
ARG A 289
THR A 273
LEU A 272
 None
 0.86A 5z86N-5bu6A:
undetectable
5z86W-5bu6A:
undetectable		 5z86N-5bu6A:
18.29
5z86W-5bu6A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 ILE A  93
ARG A 289
THR A 273
LEU A 272
 None
 0.95A 5zcoA-5bu6A:
undetectable
5zcoJ-5bu6A:
undetectable		 5zcoA-5bu6A:
18.29
5zcoJ-5bu6A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 6 ILE A  93
ARG A 289
THR A 273
LEU A 272
 None
 0.85A 5zcoN-5bu6A:
undetectable
5zcoW-5bu6A:
undetectable		 5zcoN-5bu6A:
18.29
5zcoW-5bu6A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		4 / 8 ILE A  93
ARG A 289
THR A 273
LEU A 272
 None
 0.89A 5zcqN-5bu6A:
undetectable
5zcqW-5bu6A:
undetectable		 5zcqN-5bu6A:
18.29
5zcqW-5bu6A:
11.74