SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 6 LEU A  82
ASP A 362
GLY A 331
ARG A 324
 None
 0.80A 1mt1G-5bu9A:
undetectable
1mt1J-5bu9A:
undetectable		 1mt1G-5bu9A:
15.25
1mt1J-5bu9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 6 ARG A 324
LEU A  82
ASP A 362
GLY A 331
 None
 0.82A 1n13H-5bu9A:
undetectable
1n13K-5bu9A:
undetectable		 1n13H-5bu9A:
16.62
1n13K-5bu9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 7 LEU A  82
ASP A 362
GLY A 331
ARG A 324
 None
 0.82A 1n13G-5bu9A:
undetectable
1n13J-5bu9A:
undetectable		 1n13G-5bu9A:
15.25
1n13J-5bu9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 7 ASP A 337
THR A 335
ILE A 363
PHE A  83
 None
 1.06A 2jc9A-5bu9A:
undetectable		 2jc9A-5bu9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 5 ILE A 194
LEU A 189
ALA A 145
PHE A 238
 None
 0.85A 2opxA-5bu9A:
undetectable		 2opxA-5bu9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 7 ARG A 324
LEU A  82
ASP A 362
GLY A 331
 None
 0.80A 2qqcD-5bu9A:
undetectable
2qqcE-5bu9A:
undetectable		 2qqcD-5bu9A:
16.32
2qqcE-5bu9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 8 ARG A 324
LEU A  82
ASP A 362
GLY A 331
 None
 0.73A 2qqdB-5bu9A:
undetectable
2qqdC-5bu9A:
undetectable		 2qqdB-5bu9A:
16.62
2qqdC-5bu9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 12 VAL A 118
ASN A 197
VAL A 247
GLY A 186
ALA A 190
 None
 1.14A 2x2iA-5bu9A:
4.0		 2x2iA-5bu9A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 12 VAL A 118
ASN A 197
VAL A 247
GLY A 186
ALA A 190
 None
 1.22A 2x2iC-5bu9A:
3.3		 2x2iC-5bu9A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 9 GLN A 170
ALA A 167
PHE A 224
LEU A 189
VAL A 247
 None
 1.28A 3claA-5bu9A:
undetectable		 3claA-5bu9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 12 GLU A 135
GLY A 138
ALA A 136
ASP A  72
ALA A  71
 None
 1.26A 3nvkF-5bu9A:
undetectable
3nvkJ-5bu9A:
undetectable		 3nvkF-5bu9A:
21.86
3nvkJ-5bu9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 6 ILE A 354
GLU A 358
PHE A 314
ALA A 356
 None
 1.10A 3pgyA-5bu9A:
undetectable
3pgyB-5bu9A:
undetectable		 3pgyA-5bu9A:
22.84
3pgyB-5bu9A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 6 PHE A  83
SER A 339
MET A 376
LEU A 365
 None
 1.31A 5dzka-5bu9A:
2.4
5dzko-5bu9A:
undetectable		 5dzka-5bu9A:
20.52
5dzko-5bu9A:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		4 / 6 PHE A  83
SER A 339
MET A 376
LEU A 365
 None
 1.31A 5dzke-5bu9A:
1.7
5dzks-5bu9A:
undetectable		 5dzke-5bu9A:
20.52
5dzks-5bu9A:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		3 / 3 GLY A 256
LEU A 257
HIS A 253
 None
None
GOL  A 501 (-3.8A)
 0.68A 5u63A-5bu9A:
undetectable		 5u63A-5bu9A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 12 VAL A 377
VAL A 380
SER A 371
VAL A  95
GLU A  93
 None
 1.35A 6bzoC-5bu9A:
undetectable		 6bzoC-5bu9A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5bu9 BETA-N-ACETYLHEXOSAM
INIDASE
(Beutenbergia
cavernae) 		5 / 9 ASN A 214
VAL A 205
GLY A 256
LEU A 257
VAL A 201
 None
 1.33A 6czmA-5bu9A:
undetectable
6czmB-5bu9A:
undetectable		 6czmA-5bu9A:
24.63
6czmB-5bu9A:
24.63