SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5buv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		3 / 3 TRP A 149
VAL A  58
TRP A 156
 None
 1.06A 1c4dC-5buvA:
undetectable
1c4dD-5buvA:
undetectable		 1c4dC-5buvA:
4.49
1c4dD-5buvA:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 8 TYR A  50
HIS A  63
HIS A 120
LYS A  73
 CYT  A 203 (-4.6A)
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
PO4  A 202 (-2.8A)
 1.18A 1eqbA-5buvA:
undetectable
1eqbB-5buvA:
undetectable		 1eqbA-5buvA:
17.83
1eqbB-5buvA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.35A 1gtfP-5buvA:
2.3
1gtfQ-5buvA:
3.0		 1gtfP-5buvA:
18.24
1gtfQ-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 1gtfT-5buvA:
2.9
1gtfU-5buvA:
2.3		 1gtfT-5buvA:
18.24
1gtfU-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 11 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.34A 1gtfU-5buvA:
2.3
1gtfV-5buvA:
2.3		 1gtfU-5buvA:
18.24
1gtfV-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 SER A  52
GLY A  61
HIS A  63
HIS A 120
ILE A  59
 PO4  A 201 ( 4.8A)
None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
 1.32A 1gtfL-5buvA:
2.3
1gtfV-5buvA:
2.3		 1gtfL-5buvA:
18.24
1gtfV-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 5 PHE A 154
LEU A  83
PHE A 152
MET A  62
 None
 1.26A 1wrkB-5buvA:
undetectable		 1wrkB-5buvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 8 HIS A 139
PRO A 141
ASP A 144
SER A 164
 CYT  A 203 (-3.7A)
None
None
None
 1.23A 2p02A-5buvA:
undetectable		 2p02A-5buvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 6 ARG A 109
SER A  22
PHE A  21
PRO A  19
 None
 1.29A 3jqaA-5buvA:
undetectable		 3jqaA-5buvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 6 ARG A 109
SER A  22
PHE A  21
PRO A  19
 None
 1.25A 3jqaC-5buvA:
undetectable		 3jqaC-5buvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 6 ARG A 109
SER A  22
PHE A  21
PRO A  19
 None
 1.29A 3jqaD-5buvA:
undetectable		 3jqaD-5buvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 12 LEU A 114
TRP A 156
PHE A 152
ILE A 147
GLY A  61
 None
 1.26A 3kk6B-5buvA:
undetectable		 3kk6B-5buvA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 5 GLY A  61
ASP A 167
ARG A  60
GLN A  65
 None
None
PO4  A 201 (-3.9A)
None
 1.30A 3qx3B-5buvA:
undetectable		 3qx3B-5buvA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 ILE A 131
THR A  31
SER A  18
ILE A  16
THR A 129
 None
 1.08A 3um5A-5buvA:
undetectable		 3um5A-5buvA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 ILE A 131
THR A  31
SER A  18
ILE A  16
THR A 129
 None
 1.11A 3um5B-5buvA:
undetectable		 3um5B-5buvA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 7 HIS A 139
PRO A 141
ASP A 144
SER A 164
 CYT  A 203 (-3.7A)
None
None
None
 1.24A 4ndnC-5buvA:
undetectable		 4ndnC-5buvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 7 HIS A 139
PRO A 141
ASP A 144
SER A 164
 CYT  A 203 (-3.7A)
None
None
None
 1.27A 4odjA-5buvA:
undetectable		 4odjA-5buvA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 7 HIS A 139
PRO A 141
ASP A 144
SER A 164
 CYT  A 203 (-3.7A)
None
None
None
 1.25A 5a1iA-5buvA:
undetectable		 5a1iA-5buvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 4 LEU A   8
ARG A  90
ILE A  10
ILE A 118
 None
 1.31A 5dzk2-5buvA:
undetectable
5dzkM-5buvA:
undetectable
5dzkN-5buvA:
undetectable		 5dzk2-5buvA:
2.56
5dzkM-5buvA:
19.90
5dzkN-5buvA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 4 ILE A  10
ILE A 118
ARG A  90
LEU A   8
 None
 1.18A 5dzkh-5buvA:
undetectable
5dzkn-5buvA:
undetectable
5dzkv-5buvA:
undetectable		 5dzkh-5buvA:
19.90
5dzkn-5buvA:
19.90
5dzkv-5buvA:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.34A 5eewR-5buvA:
1.1
5eewS-5buvA:
1.0		 5eewR-5buvA:
18.24
5eewS-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.34A 5eexR-5buvA:
1.1
5eexS-5buvA:
1.0		 5eexR-5buvA:
18.24
5eexS-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5eeyR-5buvA:
1.1
5eeyS-5buvA:
1.0		 5eeyR-5buvA:
18.24
5eeyS-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5eeyU-5buvA:
1.1
5eeyV-5buvA:
1.1		 5eeyU-5buvA:
18.24
5eeyV-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.34A 5eezR-5buvA:
1.1
5eezS-5buvA:
0.8		 5eezR-5buvA:
18.24
5eezS-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.32A 5eezU-5buvA:
1.0
5eezV-5buvA:
1.1		 5eezU-5buvA:
18.24
5eezV-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5ef0R-5buvA:
1.1
5ef0S-5buvA:
1.0		 5ef0R-5buvA:
18.24
5ef0S-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.32A 5ef0U-5buvA:
1.0
5ef0V-5buvA:
1.1		 5ef0U-5buvA:
18.24
5ef0V-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5ef1R-5buvA:
0.9
5ef1S-5buvA:
1.0		 5ef1R-5buvA:
18.24
5ef1S-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.32A 5ef1U-5buvA:
1.1
5ef1V-5buvA:
1.1		 5ef1U-5buvA:
18.24
5ef1V-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5ef2R-5buvA:
1.1
5ef2S-5buvA:
1.0		 5ef2R-5buvA:
18.24
5ef2S-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.32A 5ef2U-5buvA:
1.1
5ef2V-5buvA:
1.1		 5ef2U-5buvA:
18.24
5ef2V-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.33A 5ef3R-5buvA:
1.1
5ef3S-5buvA:
1.0		 5ef3R-5buvA:
18.24
5ef3S-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 10 GLY A  61
HIS A  63
HIS A 120
ILE A  59
SER A  52
 None
PO4  A 201 ( 3.8A)
PO4  A 202 (-3.9A)
None
PO4  A 201 ( 4.8A)
 1.32A 5ef3U-5buvA:
1.1
5ef3V-5buvA:
1.1		 5ef3U-5buvA:
18.24
5ef3V-5buvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 5 ASN A   9
LEU A   8
THR A  95
CYH A  13
 None
 1.39A 5eu8A-5buvA:
undetectable		 5eu8A-5buvA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		4 / 7 HIS A 139
PRO A 141
ASP A 144
SER A 164
 CYT  A 203 (-3.7A)
None
None
None
 1.25A 6g6rA-5buvA:
undetectable		 6g6rA-5buvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_B_Y70B502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 11 ASN A 105
PRO A 106
HIS A 107
GLU A  79
PHE A 122
 None
 1.38A 6h0gB-5buvA:
0.0
6h0gC-5buvA:
undetectable		 6h0gB-5buvA:
16.29
6h0gC-5buvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 5buv PUTATIVE EPIMERASE
(Yersinia
enterocolitica) 		5 / 12 ASN A 105
PRO A 106
HIS A 107
GLU A  79
PHE A 122
 None
 1.42A 6h0gE-5buvA:
undetectable
6h0gF-5buvA:
undetectable		 6h0gE-5buvA:
16.29
6h0gF-5buvA:
14.29