SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5bux 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Yersinia
pestis) 		5 / 12 LEU A  38
ALA A  73
LEU A  16
CYH A 145
THR A 125
 None
 1.27A 2aa6B-5buxA:
undetectable		 2aa6B-5buxA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5bux 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Yersinia
pestis) 		4 / 5 GLY A  57
PRO A 107
VAL A 106
ILE A  60
 None
 1.00A 2aoiA-5buxA:
undetectable		 2aoiA-5buxA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 5bux 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Yersinia
pestis) 		3 / 3 GLU A  11
LEU A  14
ASP A  15
 None
 0.34A 3ko0A-5buxA:
undetectable		 3ko0A-5buxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 5bux 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Yersinia
pestis) 		3 / 3 GLU A  11
LEU A  14
ASP A  15
 None
 0.41A 3ko0T-5buxA:
undetectable		 3ko0T-5buxA:
21.24