SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		4 / 5 GLN A  90
THR A  94
HIS A 178
LEU A 179
 None
 1.37A 2zj0A-5bv5A:
undetectable		 2zj0A-5bv5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 10 LEU A 360
THR A 346
ASP A 224
ARG A 227
ILE A 343
 None
 1.50A 3bexC-5bv5A:
undetectable
3bexD-5bv5A:
undetectable		 3bexC-5bv5A:
23.75
3bexD-5bv5A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		4 / 6 GLU A 246
PRO A 300
ARG A 249
HIS A 307
 None
 1.08A 3ltwA-5bv5A:
undetectable		 3ltwA-5bv5A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		4 / 5 ILE A 128
THR A 102
THR A 103
PHE A  98
 None
 1.21A 3snfA-5bv5A:
undetectable		 3snfA-5bv5A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		4 / 4 PRO A 124
LEU A 121
ILE A 110
ARG A 337
 None
 1.37A 3w1wA-5bv5A:
undetectable		 3w1wA-5bv5A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 12 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.13A 5iqbA-5bv5A:
undetectable		 5iqbA-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 11 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.13A 5iqbB-5bv5A:
0.5		 5iqbB-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_C_KANC600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 11 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.13A 5iqbC-5bv5A:
1.9		 5iqbC-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 12 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.13A 5iqbD-5bv5A:
1.7		 5iqbD-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 12 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.36A 5iqdC-5bv5A:
0.2		 5iqdC-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 12 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.37A 5iqeC-5bv5A:
1.9		 5iqeC-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 12 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.28A 5iqeD-5bv5A:
1.8		 5iqeD-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 10 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.28A 6c5uA-5bv5A:
1.8		 6c5uA-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 10 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.31A 6c5uD-5bv5A:
1.7		 6c5uD-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 10 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.28A 6cggB-5bv5A:
0.0		 6cggB-5bv5A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 5bv5 CYTOCHROME P450 119
(Sulfolobus
solfataricus) 		5 / 11 ASP A 224
SER A 251
ASN A 355
TYR A 250
GLU A 296
 None
 1.28A 6cggD-5bv5A:
1.7		 6cggD-5bv5A:
23.77