SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.25A 1d1vA-5bv9A:
undetectable
1d1vB-5bv9A:
undetectable		 1d1vA-5bv9A:
21.54
1d1vB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.24A 1d1wA-5bv9A:
0.0
1d1wB-5bv9A:
undetectable		 1d1wA-5bv9A:
21.54
1d1wB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.23A 1d1xA-5bv9A:
undetectable
1d1xB-5bv9A:
undetectable		 1d1xA-5bv9A:
21.54
1d1xB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 1dm8A-5bv9A:
undetectable
1dm8B-5bv9A:
undetectable		 1dm8A-5bv9A:
21.54
1dm8B-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 1dmiA-5bv9A:
undetectable
1dmiB-5bv9A:
undetectable		 1dmiA-5bv9A:
21.54
1dmiB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 1fopA-5bv9A:
undetectable
1fopB-5bv9A:
undetectable		 1fopA-5bv9A:
21.54
1fopB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 TRP A 362
TYR A 393
LEU A 292
 None
GOL  A 816 (-3.6A)
None
 0.98A 1kxhA-5bv9A:
undetectable		 1kxhA-5bv9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.24A 1nseA-5bv9A:
undetectable
1nseB-5bv9A:
undetectable		 1nseA-5bv9A:
21.54
1nseB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.22A 1nseA-5bv9A:
undetectable
1nseB-5bv9A:
undetectable		 1nseA-5bv9A:
21.54
1nseB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 ASP A 195
GLY A 301
SER A 310
ALA A 218
ALA A 217
 None
None
None
EDO  A 807 ( 3.8A)
None
 1.19A 1nw5A-5bv9A:
undetectable		 1nw5A-5bv9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.30A 1p6lA-5bv9A:
undetectable
1p6lB-5bv9A:
undetectable		 1p6lA-5bv9A:
21.37
1p6lB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.24A 1p6nA-5bv9A:
undetectable
1p6nB-5bv9A:
0.0		 1p6nA-5bv9A:
21.37
1p6nB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 LEU A 260
TYR A 322
GLY A 263
ASN A 224
TYR A 360
 None
 1.22A 1pj7A-5bv9A:
undetectable		 1pj7A-5bv9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.26A 1rs8A-5bv9A:
undetectable
1rs8B-5bv9A:
0.0		 1rs8A-5bv9A:
21.37
1rs8B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 1rs8A-5bv9A:
undetectable
1rs8B-5bv9A:
0.0		 1rs8A-5bv9A:
21.37
1rs8B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.29A 1rs9A-5bv9A:
0.0
1rs9B-5bv9A:
undetectable		 1rs9A-5bv9A:
21.37
1rs9B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 GLY A 304
GLY A 302
ARG A 221
TYR A 222
PRO A  84
 EDO  A 807 ( 3.8A)
None
EDO  A 808 ( 4.8A)
None
None
 1.24A 1y4lA-5bv9A:
undetectable		 1y4lA-5bv9A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.28A 1zztA-5bv9A:
0.0
1zztB-5bv9A:
0.0		 1zztA-5bv9A:
20.95
1zztB-5bv9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.30A 1zztA-5bv9A:
0.0
1zztB-5bv9A:
0.0		 1zztA-5bv9A:
20.95
1zztB-5bv9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 GLY A 413
PHE A 412
ASP A 530
THR A 528
 None
 1.18A 2aouB-5bv9A:
undetectable		 2aouB-5bv9A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 PHE A 640
PHE A 598
TYR A  42
TYR A 158
 None
 1.44A 2aoxA-5bv9A:
undetectable		 2aoxA-5bv9A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 SER A 342
TYR A 262
GLN A 323
ASP A 348
 None
 1.38A 2cl5B-5bv9A:
undetectable		 2cl5B-5bv9A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 2nseA-5bv9A:
undetectable
2nseB-5bv9A:
undetectable		 2nseA-5bv9A:
21.54
2nseB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 5 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 2nseA-5bv9A:
0.0
2nseB-5bv9A:
0.0		 2nseA-5bv9A:
21.54
2nseB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 4 SER A 365
GLY A 368
HIS A 319
ASP A 227
 None
 1.36A 2oxtC-5bv9A:
undetectable		 2oxtC-5bv9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 LEU A 455
ASN A 452
ARG A 565
 None
 0.88A 2qhfA-5bv9A:
undetectable		 2qhfA-5bv9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ALA A 690
THR A 691
ALA A 694
ARG A 698
 None
 0.72A 2ql8A-5bv9A:
undetectable
2ql8B-5bv9A:
undetectable		 2ql8A-5bv9A:
13.06
2ql8B-5bv9A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 SER A 639
VAL A 603
PHE A 205
ILE A 619
ASN A 617
 None
 1.17A 2vdyB-5bv9A:
undetectable		 2vdyB-5bv9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 TRP A 150
GLN A 177
TRP A 185
 ACT  A 814 (-2.8A)
None
None
 1.21A 2vqyA-5bv9A:
undetectable		 2vqyA-5bv9A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 10 ILE A 460
TYR A 580
LEU A 538
VAL A 537
LEU A 541
 None
 1.46A 2w98A-5bv9A:
undetectable		 2w98A-5bv9A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 SER A 342
TYR A 262
GLN A 323
ASP A 348
 None
 1.41A 2zvjA-5bv9A:
undetectable		 2zvjA-5bv9A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 5 TYR A 360
ALA A 327
ALA A 423
TYR A 427
 None
 1.27A 3d91A-5bv9A:
undetectable		 3d91A-5bv9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 3dqsA-5bv9A:
undetectable
3dqsB-5bv9A:
undetectable		 3dqsA-5bv9A:
21.37
3dqsB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.26A 3dqtA-5bv9A:
undetectable
3dqtB-5bv9A:
undetectable		 3dqtA-5bv9A:
21.37
3dqtB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 4 GLN A 356
GLN A 323
GLY A 321
HIS A 319
 None
 1.48A 3huoA-5bv9A:
undetectable		 3huoA-5bv9A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 ASN A 410
ASP A 399
ARG A 631
 GOL  A 818 (-3.1A)
ACT  A 813 (-3.2A)
None
 0.72A 3k13C-5bv9A:
undetectable		 3k13C-5bv9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 TYR A 693
TRP A 578
LEU A  10
ASN A 581
 None
 1.37A 3k8mB-5bv9A:
undetectable		 3k8mB-5bv9A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.38A 3n5vA-5bv9A:
undetectable
3n5vB-5bv9A:
undetectable		 3n5vA-5bv9A:
20.31
3n5vB-5bv9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 LYS A 600
ARG A 597
ASP A 115
 None
CA  A 801 ( 4.7A)
None
 1.38A 3o7wA-5bv9A:
undetectable		 3o7wA-5bv9A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 LEU A 702
LEU A 574
ALA A 694
ALA A 692
TYR A 696
 None
 1.13A 3vw7A-5bv9A:
undetectable		 3vw7A-5bv9A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.23A 3wg7C-5bv9A:
undetectable
3wg7N-5bv9A:
undetectable
3wg7P-5bv9A:
undetectable		 3wg7C-5bv9A:
16.00
3wg7N-5bv9A:
20.55
3wg7P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.20A 3x2qA-5bv9A:
undetectable
3x2qC-5bv9A:
undetectable
3x2qP-5bv9A:
undetectable		 3x2qA-5bv9A:
20.55
3x2qC-5bv9A:
16.00
3x2qP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 9 GLY A 413
ASN A 502
SER A 685
GLY A 536
ASP A 534
 None
None
CBI  A 804 ( 4.7A)
None
CBI  A 804 (-3.0A)
 1.30A 3ztvA-5bv9A:
undetectable		 3ztvA-5bv9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.30A 4cu1A-5bv9A:
0.0
4cu1B-5bv9A:
undetectable		 4cu1A-5bv9A:
21.37
4cu1B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.29A 4cu1A-5bv9A:
0.0
4cu1B-5bv9A:
undetectable		 4cu1A-5bv9A:
21.37
4cu1B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 4cwvA-5bv9A:
undetectable
4cwvB-5bv9A:
0.0		 4cwvA-5bv9A:
21.37
4cwvB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 4d33A-5bv9A:
undetectable
4d33B-5bv9A:
undetectable		 4d33A-5bv9A:
21.37
4d33B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 4d33A-5bv9A:
undetectable
4d33B-5bv9A:
undetectable		 4d33A-5bv9A:
21.37
4d33B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.29A 4d34A-5bv9A:
undetectable
4d34B-5bv9A:
undetectable		 4d34A-5bv9A:
21.37
4d34B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.29A 4d37A-5bv9A:
undetectable
4d37B-5bv9A:
0.0		 4d37A-5bv9A:
21.37
4d37B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.30A 4d37A-5bv9A:
undetectable
4d37B-5bv9A:
0.0		 4d37A-5bv9A:
21.37
4d37B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.29A 4d38A-5bv9A:
undetectable
4d38B-5bv9A:
undetectable		 4d38A-5bv9A:
21.37
4d38B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.29A 4d3aA-5bv9A:
undetectable
4d3aB-5bv9A:
undetectable		 4d3aA-5bv9A:
21.37
4d3aB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ILE A  83
PRO A  84
GLY A 300
GLN A 177
 None
 0.71A 4g0uB-5bv9A:
undetectable		 4g0uB-5bv9A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.28A 4imxA-5bv9A:
undetectable
4imxB-5bv9A:
undetectable		 4imxA-5bv9A:
21.51
4imxB-5bv9A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 SER A 332
LEU A 331
GLN A 356
MET A 264
GLY A 263
 None
 1.45A 4j7xA-5bv9A:
undetectable		 4j7xA-5bv9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 SER A 332
LEU A 331
GLN A 356
MET A 264
GLY A 263
 None
 1.47A 4j7xF-5bv9A:
undetectable		 4j7xF-5bv9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.28A 4jsmA-5bv9A:
1.7
4jsmB-5bv9A:
undetectable		 4jsmA-5bv9A:
21.37
4jsmB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 GLU A 241
TRP A 238
LYS A 335
 ACT  A 810 (-3.2A)
None
None
 1.48A 4k7aA-5bv9A:
undetectable		 4k7aA-5bv9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 GLU A 695
TRP A 238
LYS A   4
 None
 1.48A 4k7aA-5bv9A:
undetectable		 4k7aA-5bv9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.26A 4luwA-5bv9A:
undetectable
4luwB-5bv9A:
undetectable		 4luwA-5bv9A:
21.37
4luwB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 ILE A 313
ARG A 178
PRO A 216
LEU A 121
THR A 223
 None
None
None
None
ACT  A 814 ( 4.9A)
 0.77A 4m6kA-5bv9A:
undetectable		 4m6kA-5bv9A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 10 TYR A 160
ASP A 153
ALA A 187
GLY A 614
PHE A 613
 None
 1.34A 4mmdA-5bv9A:
1.4		 4mmdA-5bv9A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.30A 4nosC-5bv9A:
undetectable
4nosD-5bv9A:
undetectable		 4nosC-5bv9A:
19.86
4nosD-5bv9A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 9 ALA A 396
THR A 375
ALA A 374
GLY A 275
GLY A 273
 None
MLI  A 805 ( 4.1A)
None
None
EDO  A 809 (-4.0A)
 1.14A 4qwuY-5bv9A:
undetectable
4qwuZ-5bv9A:
undetectable		 4qwuY-5bv9A:
16.22
4qwuZ-5bv9A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 12 ASN A 376
GLU A 398
GLY A 373
GLN A 415
HIS A 319
 None
MLI  A 805 ( 3.2A)
None
None
None
 1.34A 4xucA-5bv9A:
undetectable		 4xucA-5bv9A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 5adnA-5bv9A:
0.0
5adnB-5bv9A:
undetectable		 5adnA-5bv9A:
21.37
5adnB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.24A 5adnA-5bv9A:
0.0
5adnB-5bv9A:
undetectable		 5adnA-5bv9A:
21.37
5adnB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 5 TYR A 291
GLY A 287
TYR A 265
GLY A 314
 None
 1.04A 5ayfA-5bv9A:
undetectable		 5ayfA-5bv9A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.18A 5b1bA-5bv9A:
undetectable
5b1bC-5bv9A:
undetectable
5b1bP-5bv9A:
undetectable		 5b1bA-5bv9A:
20.55
5b1bC-5bv9A:
16.00
5b1bP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 5 HIS A 317
SER A 316
ILE A 313
TYR A 268
 None
None
None
EDO  A 808 (-4.6A)
 1.32A 5fuqA-5bv9A:
undetectable
5fuqB-5bv9A:
undetectable		 5fuqA-5bv9A:
18.19
5fuqB-5bv9A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.26A 5fvyA-5bv9A:
undetectable
5fvyB-5bv9A:
undetectable		 5fvyA-5bv9A:
21.37
5fvyB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_1
(TUBULIN BETA-2B
CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 9 LYS A 431
VAL A 430
ASP A 434
TYR A 427
PHE A 547
 ACT  A 810 (-4.9A)
None
None
None
None
 1.48A 5j2tB-5bv9A:
undetectable		 5j2tB-5bv9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.39A 5unvA-5bv9A:
undetectable
5unvB-5bv9A:
undetectable		 5unvA-5bv9A:
20.31
5unvB-5bv9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.28A 5uo8A-5bv9A:
undetectable
5uo8B-5bv9A:
undetectable		 5uo8A-5bv9A:
21.23
5uo8B-5bv9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 VAL A 603
ILE A 647
SER A 623
THR A 638
 None
 1.05A 5vkqA-5bv9A:
2.6
5vkqD-5bv9A:
2.6		 5vkqA-5bv9A:
17.33
5vkqD-5bv9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.34A 5vujA-5bv9A:
undetectable
5vujB-5bv9A:
undetectable		 5vujA-5bv9A:
20.31
5vujB-5bv9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 5vv6A-5bv9A:
undetectable
5vv6B-5bv9A:
undetectable		 5vv6A-5bv9A:
21.37
5vv6B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 5vv8A-5bv9A:
undetectable
5vv8B-5bv9A:
undetectable		 5vv8A-5bv9A:
21.37
5vv8B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 5vv9A-5bv9A:
undetectable
5vv9B-5bv9A:
0.0		 5vv9A-5bv9A:
21.37
5vv9B-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.31A 5vvaA-5bv9A:
undetectable
5vvaB-5bv9A:
undetectable		 5vvaA-5bv9A:
21.37
5vvaB-5bv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W5V_A_ANWA701_0
(SERINE/THREONINE-PRO
TEIN KINASE TBK1)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 9 LEU A  71
ALA A 235
GLY A  62
THR A  65
THR A 691
 None
 1.45A 5w5vA-5bv9A:
undetectable		 5w5vA-5bv9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.18A 5w97A-5bv9A:
2.3
5w97C-5bv9A:
undetectable
5w97c-5bv9A:
undetectable		 5w97A-5bv9A:
20.55
5w97C-5bv9A:
16.00
5w97c-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.16A 5w97C-5bv9A:
undetectable
5w97a-5bv9A:
2.3
5w97c-5bv9A:
undetectable		 5w97C-5bv9A:
16.00
5w97a-5bv9A:
20.55
5w97c-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.20A 5wauC-5bv9A:
undetectable
5waua-5bv9A:
1.4
5wauc-5bv9A:
undetectable		 5wauC-5bv9A:
16.00
5waua-5bv9A:
20.55
5wauc-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.17A 5x19A-5bv9A:
2.3
5x19C-5bv9A:
undetectable
5x19P-5bv9A:
undetectable		 5x19A-5bv9A:
20.55
5x19C-5bv9A:
16.00
5x19P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.19A 5x1bA-5bv9A:
2.0
5x1bC-5bv9A:
undetectable
5x1bP-5bv9A:
undetectable		 5x1bA-5bv9A:
20.55
5x1bC-5bv9A:
16.00
5x1bP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.18A 5x1fA-5bv9A:
undetectable
5x1fC-5bv9A:
undetectable
5x1fP-5bv9A:
undetectable		 5x1fA-5bv9A:
20.55
5x1fC-5bv9A:
16.00
5x1fP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.21A 5xdqA-5bv9A:
2.1
5xdqC-5bv9A:
undetectable
5xdqP-5bv9A:
undetectable		 5xdqA-5bv9A:
20.55
5xdqC-5bv9A:
16.00
5xdqP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.24A 5z84C-5bv9A:
undetectable
5z84N-5bv9A:
3.2
5z84P-5bv9A:
undetectable		 5z84C-5bv9A:
16.00
5z84N-5bv9A:
20.55
5z84P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.22A 5z85A-5bv9A:
3.1
5z85C-5bv9A:
undetectable
5z85P-5bv9A:
undetectable		 5z85A-5bv9A:
20.55
5z85C-5bv9A:
16.00
5z85P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.23A 5z85C-5bv9A:
undetectable
5z85N-5bv9A:
3.3
5z85P-5bv9A:
undetectable		 5z85C-5bv9A:
16.00
5z85N-5bv9A:
20.55
5z85P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.21A 5z86A-5bv9A:
1.1
5z86C-5bv9A:
undetectable
5z86P-5bv9A:
undetectable		 5z86A-5bv9A:
20.55
5z86C-5bv9A:
16.00
5z86P-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.22A 5zcpA-5bv9A:
2.3
5zcpC-5bv9A:
undetectable
5zcpP-5bv9A:
undetectable		 5zcpA-5bv9A:
20.55
5zcpC-5bv9A:
16.00
5zcpP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 LEU A 242
HIS A  12
THR A  65
TYR A  64
 None
 1.21A 5zcpC-5bv9A:
undetectable
5zcpN-5bv9A:
3.3
5zcpP-5bv9A:
undetectable		 5zcpC-5bv9A:
16.00
5zcpN-5bv9A:
20.55
5zcpP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 8 HIS A  12
THR A  65
TYR A  64
LEU A 242
 None
 1.22A 5zcqA-5bv9A:
2.3
5zcqC-5bv9A:
undetectable
5zcqP-5bv9A:
undetectable		 5zcqA-5bv9A:
20.55
5zcqC-5bv9A:
16.00
5zcqP-5bv9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 VAL A 326
TYR A 237
GLU A 420
 None
 0.73A 5zmqD-5bv9A:
undetectable
5zmqE-5bv9A:
undetectable		 5zmqD-5bv9A:
13.36
5zmqE-5bv9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		3 / 3 GLN A 234
TRP A  56
VAL A  59
 None
 1.08A 6auuA-5bv9A:
undetectable		 6auuA-5bv9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.25A 6av6C-5bv9A:
0.0
6av6D-5bv9A:
0.0		 6av6C-5bv9A:
8.31
6av6D-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 6av7A-5bv9A:
undetectable
6av7B-5bv9A:
undetectable		 6av7A-5bv9A:
8.31
6av7B-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 6av7C-5bv9A:
undetectable
6av7D-5bv9A:
0.0		 6av7C-5bv9A:
8.31
6av7D-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.27A 6cieA-5bv9A:
0.0
6cieB-5bv9A:
undetectable		 6cieA-5bv9A:
8.31
6cieB-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.28A 6cieA-5bv9A:
undetectable
6cieB-5bv9A:
undetectable		 6cieA-5bv9A:
8.31
6cieB-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.25A 6cieC-5bv9A:
undetectable
6cieD-5bv9A:
0.0		 6cieC-5bv9A:
8.31
6cieD-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.24A 6cifA-5bv9A:
0.0
6cifB-5bv9A:
0.0		 6cifA-5bv9A:
8.31
6cifB-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 7 ARG A 644
TRP A 185
PHE A 640
GLU A 186
 None
None
None
CA  A 801 (-2.3A)
 1.26A 6cifC-5bv9A:
undetectable
6cifD-5bv9A:
undetectable		 6cifC-5bv9A:
8.31
6cifD-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.25A 6cifC-5bv9A:
0.0
6cifD-5bv9A:
undetectable		 6cifC-5bv9A:
8.31
6cifD-5bv9A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 4 ARG A 592
GLU A 590
GLU A  38
ARG A 682
 CBI  A 804 ( 4.5A)
None
CBI  A 804 (-3.5A)
CBI  A 804 (-3.5A)
 1.09A 6fk2A-5bv9A:
undetectable		 6fk2A-5bv9A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		5 / 10 ASP A 130
GLY A 134
GLU A 135
ASN A 143
PHE A 259
 None
 1.42A 6nqaK-5bv9A:
undetectable		 6nqaK-5bv9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.29A 8nseA-5bv9A:
undetectable
8nseB-5bv9A:
undetectable		 8nseA-5bv9A:
21.54
8nseB-5bv9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE
(Bacillus
pumilus) 		4 / 6 TRP A 185
PHE A 640
GLU A 186
ARG A 644
 None
None
CA  A 801 (-2.3A)
None
 1.27A 9nseA-5bv9A:
undetectable
9nseB-5bv9A:
undetectable		 9nseA-5bv9A:
21.54
9nseB-5bv9A:
21.54