SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
PRO A  39
THR A  54
THR A  57
TYR A 129
 None
 0.94A 1cbrA-5bvqA:
18.4		 1cbrA-5bvqA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
PRO A  39
THR A  54
THR A  57
TYR A 129
 None
 0.94A 1cbrB-5bvqA:
18.4		 1cbrB-5bvqA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
PRO A  39
THR A  54
THR A  57
TYR A 129
 None
 1.01A 1cbsA-5bvqA:
18.1		 1cbsA-5bvqA:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 LEU A  24
ALA A  34
THR A  57
ASP A  77
ILE A 105
 None
 0.92A 1tw4A-5bvqA:
18.5		 1tw4A-5bvqA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
PRO A  39
THR A  54
THR A  57
TYR A 129
 None
 1.05A 2fr3A-5bvqA:
18.1		 2fr3A-5bvqA:
38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 ILE A  50
ILE A  43
LEU A  92
ASN A  93
VAL A 116
 None
 0.88A 2nnhA-5bvqA:
undetectable		 2nnhA-5bvqA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 10 ILE A  50
ILE A  43
LEU A  92
ASN A  93
VAL A 116
 None
 0.89A 2nnhB-5bvqA:
undetectable		 2nnhB-5bvqA:
13.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
VAL A  26
ALA A  34
THR A  54
CYH A 118
 None
 1.05A 2qm9A-5bvqA:
23.5		 2qm9A-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		9 / 12 PHE A  17
VAL A  26
ALA A  34
THR A  61
ALA A  76
ASP A  77
ARG A  79
CYH A 118
TYR A 129
 None
 0.50A 2qm9A-5bvqA:
23.5		 2qm9A-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		8 / 12 PHE A  17
VAL A  26
ALA A  34
THR A  61
ALA A  76
ASP A  77
ARG A 127
TYR A 129
 None
 1.28A 2qm9A-5bvqA:
23.5		 2qm9A-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		4 / 4 TYR A  20
MET A  21
PRO A  39
ILE A 105
 None
 0.55A 2qm9A-5bvqA:
23.5		 2qm9A-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		6 / 12 PHE A  17
TYR A  20
VAL A  26
THR A  54
ILE A 105
CYH A 118
 None
 1.02A 2qm9B-5bvqA:
24.2		 2qm9B-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		9 / 12 PHE A  17
TYR A  20
VAL A  26
THR A  61
ALA A  76
ARG A  79
ILE A 105
CYH A 118
TYR A 129
 None
 0.41A 2qm9B-5bvqA:
24.2		 2qm9B-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		6 / 12 PHE A  17
VAL A  26
THR A  61
ALA A  76
ARG A 127
TYR A 129
 None
 1.38A 2qm9B-5bvqA:
24.2		 2qm9B-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		4 / 4 MET A  21
PRO A  39
ASP A  77
ARG A 107
 None
 0.47A 2qm9B-5bvqA:
24.2		 2qm9B-5bvqA:
73.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		6 / 12 PHE A  17
MET A  21
VAL A  26
ASP A  77
ARG A 127
TYR A 129
 None
 1.32A 3p6gA-5bvqA:
23.4		 3p6gA-5bvqA:
75.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		11 / 12 PHE A  17
MET A  21
VAL A  26
PRO A  39
ASP A  77
ARG A  79
ILE A 105
ARG A 107
VAL A 116
CYH A 118
TYR A 129
 None
 0.71A 3p6gA-5bvqA:
23.4		 3p6gA-5bvqA:
75.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 7 PHE A  17
MET A  21
ASP A  77
ARG A 127
TYR A 129
 None
 1.46A 3p6hA-5bvqA:
23.5		 3p6hA-5bvqA:
75.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		6 / 7 PHE A  17
MET A  21
ASP A  77
ILE A 105
VAL A 116
TYR A 129
 None
 0.65A 3p6hA-5bvqA:
23.5		 3p6hA-5bvqA:
75.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 8 ILE A  85
GLN A  94
PHE A  65
THR A  54
THR A  61
 None
 1.16A 4n16A-5bvqA:
undetectable		 4n16A-5bvqA:
18.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5bvq FATTY ACID-BINDING
PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  17
TYR A  20
VAL A  26
ALA A  34
ILE A  52
 None
 0.75A 5hbsA-5bvqA:
19.6		 5hbsA-5bvqA:
37.78