SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 ALA A  39
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 (-3.3A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 1.09A 1cbrA-5bvtA:
18.9		 1cbrA-5bvtA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 0.73A 1cbrA-5bvtA:
18.9		 1cbrA-5bvtA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 ALA A  39
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 (-3.3A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 1.09A 1cbrB-5bvtA:
18.9		 1cbrB-5bvtA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 0.73A 1cbrB-5bvtA:
18.9		 1cbrB-5bvtA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 0.76A 1cbsA-5bvtA:
18.7		 1cbsA-5bvtA:
38.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
THR A  56
GLY A  80
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
None
None
PAM  A 201 ( 4.6A)
None
 0.86A 2cbrA-5bvtA:
19.1		 2cbrA-5bvtA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
PRO A  41
THR A  56
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 4.8A)
None
PAM  A 201 ( 4.6A)
None
 0.77A 2fr3A-5bvtA:
18.9		 2fr3A-5bvtA:
38.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 VAL A  54
PHE A  67
THR A  77
VAL A  87
LEU A  95
 None
 0.81A 2jn3A-5bvtA:
18.8		 2jn3A-5bvtA:
29.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		8 / 12 PHE A  19
VAL A  28
SER A  58
ASP A  79
ARG A  81
CYH A 121
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
None
PAM  A 201 ( 3.9A)
PAM  A 201 (-4.0A)
None
PAM  A 201 ( 4.0A)
PAM  A 201 ( 4.6A)
None
 0.55A 2qm9A-5bvtA:
24.8		 2qm9A-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		6 / 12 VAL A  28
SER A  58
ASP A  79
CYH A 128
ARG A 130
TYR A 132
 None
PAM  A 201 ( 3.9A)
PAM  A 201 (-4.0A)
None
PAM  A 201 ( 4.6A)
None
 1.43A 2qm9A-5bvtA:
24.8		 2qm9A-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 VAL A  28
THR A  56
ASP A  79
ARG A  81
CYH A 121
 None
None
PAM  A 201 (-4.0A)
None
PAM  A 201 ( 4.0A)
 1.07A 2qm9A-5bvtA:
24.8		 2qm9A-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		4 / 4 TYR A  22
MET A  23
PRO A  41
ILE A 108
 None
PAM  A 201 ( 3.8A)
PAM  A 201 ( 4.8A)
PAM  A 201 ( 4.7A)
 0.41A 2qm9A-5bvtA:
24.8		 2qm9A-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 12 PHE A  19
TYR A  22
SER A  63
ILE A 108
CYH A 121
 PAM  A 201 ( 4.9A)
None
None
PAM  A 201 ( 4.7A)
PAM  A 201 ( 4.0A)
 1.25A 2qm9B-5bvtA:
25.2		 2qm9B-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		9 / 12 PHE A  19
TYR A  22
VAL A  28
SER A  58
ARG A  81
ILE A 108
CYH A 121
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
None
None
PAM  A 201 ( 3.9A)
None
PAM  A 201 ( 4.7A)
PAM  A 201 ( 4.0A)
PAM  A 201 ( 4.6A)
None
 0.49A 2qm9B-5bvtA:
25.2		 2qm9B-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		6 / 12 TYR A  22
VAL A  28
THR A  56
ARG A  81
ILE A 108
CYH A 121
 None
None
None
None
PAM  A 201 ( 4.7A)
PAM  A 201 ( 4.0A)
 0.97A 2qm9B-5bvtA:
25.2		 2qm9B-5bvtA:
47.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		4 / 4 MET A  23
PRO A  41
ASP A  79
ARG A 110
 PAM  A 201 ( 3.8A)
PAM  A 201 ( 4.8A)
PAM  A 201 (-4.0A)
PAM  A 201 ( 4.6A)
 0.25A 2qm9B-5bvtA:
25.2		 2qm9B-5bvtA:
47.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		4 / 7 PHE A   7
LEU A  95
LEU A  69
LEU A  89
 None
 0.77A 3bgdB-5bvtA:
undetectable		 3bgdB-5bvtA:
19.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		12 / 12 PHE A  19
MET A  23
VAL A  28
PRO A  41
ASP A  79
ARG A  81
ILE A 108
ARG A 110
VAL A 119
CYH A 121
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 3.8A)
None
PAM  A 201 ( 4.8A)
PAM  A 201 (-4.0A)
None
PAM  A 201 ( 4.7A)
PAM  A 201 ( 4.6A)
None
PAM  A 201 ( 4.0A)
PAM  A 201 ( 4.6A)
None
 0.65A 3p6gA-5bvtA:
24.5		 3p6gA-5bvtA:
52.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		8 / 12 PHE A  19
MET A  23
VAL A  28
PRO A  41
ASP A  79
CYH A 128
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 3.8A)
None
PAM  A 201 ( 4.8A)
PAM  A 201 (-4.0A)
None
PAM  A 201 ( 4.6A)
None
 1.08A 3p6gA-5bvtA:
24.5		 3p6gA-5bvtA:
52.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		7 / 7 PHE A  19
MET A  23
ASP A  79
ILE A 108
VAL A 119
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 3.8A)
PAM  A 201 (-4.0A)
PAM  A 201 ( 4.7A)
None
PAM  A 201 ( 4.6A)
None
 0.46A 3p6hA-5bvtA:
24.5		 3p6hA-5bvtA:
52.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		4 / 6 TYR A  22
GLU A  75
THR A  77
GLN A  99
 None
 0.73A 4qztA-5bvtA:
20.1		 4qztA-5bvtA:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		4 / 6 TYR A  22
GLU A  75
THR A  77
GLN A  99
 None
 0.70A 4qzuC-5bvtA:
20.2		 4qzuC-5bvtA:
32.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN
(Pygoscelis
papua) 		5 / 9 ASP A  50
ALA A   3
ILE A   4
PHE A  67
GLY A  70
 None
 1.36A 6awqA-5bvtA:
undetectable		 6awqA-5bvtA:
12.64